On top of the null effect on survival and stroke, LAA occlusion had no significant effect on procedure times and length of stay. Endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation, American Pharmacists Association, American Society for Nutrition, American Society for Parenteral and Enteral Nutrition, American Society for Preventive Cardiology, American Society of Hypertension, Association of Black Cardiologists, National Lipid Association, Preventive Cardiovascular Nurses Association, The Endocrine Society, and WomenHeart: The National Coalition for Women With Heart Disease, Harmon S. Jordan, ScD; Karima A. Kendall, PhD; Linda J. Lux; Roycelynn Mentor-Marcel, PhD, MPH; Laura C. Morgan, MA; Michael G. Trisolini, PhD, MBA; Janusz Wnek, PhD, Jeffrey L. Anderson, MD, FACC, FAHA, Chair; Jonathan L. Halperin, MD, FACC, FAHA, Chair-Elect; Nancy M. Albert, PhD, CCNS, CCRN, FAHA; Biykem Bozkurt, MD, PhD, FACC, FAHA; Ralph G. Brindis, MD, MPH, MACC; Lesley H. Curtis, PhD, FAHA; David DeMets, PhD; Judith S. Hochman, MD, FACC, FAHA; Richard J. Kovacs, MD, FACC, FAHA; E. Magnus Ohman, MD, FACC; Susan J. Pressler, PhD, RN, FAAN, FAHA; Frank W. Sellke, MD, FACC, FAHA; Win-Kuang Shen, MD, FACC, FAHA, Sidney C. Smith, Jr, MD, FACC, FAHA; Chair, Gordon F. Tomaselli, MD, FACC, FAHA, Co-Chair. The ultimate decision about care of a particular patient must be made by the healthcare provider and patient in light of the circumstances presented by that patient. Results from the Swedish obese subjects study. ES2. The guideline was reviewed by the ACC/AHA Task Force and approved by the ACC Board of Trustees, the AHA Science Advisory and Coordinating Committee, and The Obesity Society. Most measures of health-related quality of life are improved at 2 and 10 years after bariatric surgery. The next steps in developing clinical practice guidelines for prevention. Results from a post-hoc analysis of patients on hemodialysis in the ongoing ILLUMINATE-C Phase 3 open-label study of lumasiran in patients with advanced primary hyperoxaluria type 1 (PH1) were presented at the International Pediatric Nephrology Association (IPNA) Congress (Sept. 7-11, 2022). However, CQ1 includes some ESs on the efficacy of orlistat because the effect of pharmacotherapy on weight loss was included in its evidence review. Differentiated long-term effects of intentional weight loss on diabetes and hypertension. Published online October 2, 2022. NHLBI Grading of the Strength of Recommendations. Identified (a priori) inclusion/exclusion (I/E) criteria for each CQ. Effects of exercise-focused versus weight-focused maintenance programs on the management of obesity. Weve been pioneering RNAi therapeutics since 2002 and are excited to share our ongoing scientific progress. ES2c (Long-Term Weight Loss). Studies should examine the independent and combined effects of BMI and waist circumference to determine if both in combination are better at predicting elevated risk than either alone. Follow Steve Stiles on Twitter: @SteveStiles2. If youre registered for ISHLT2022 Virtual On Demand, or you attended the conference in-person in Boston, click the button below to access the on-demand platform. Web2022. Four-year weight losses in the Look AHEAD study: factors associated with long-term success. All abstracts submitted must comply with the guidelines to be considered for acceptance. Check out our web page for a full conference listing and registration offerings! 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. Pohybovali jsme se ve stavebnictv, investovali do zadluench firem a nemovitost. Thus, James Januzzi, MD, and colleagues examined this association among 794 participants of the Prospective Study of Biomarkers, Symptom Improvement, and Ventricular Remodeling During Sacubitril/Valsartan Therapy for Heart Failure (PROVE-HF) who had HF and left ventricular ejection fraction (LVEF) less than 40% and among whom sac/val was initiated and titrated to a maximally tolerated dose. Of the 1422 articles screened against the I/E criteria, 438 full-text articles were retrieved to further assess eligibility. Appendix 1. Low-intensity, on-site comprehensive lifestyle interventions, which provide less-than-monthly treatment sessions, do not consistently produce weight loss when compared with usual care. For this reason, the Expert Panel did not develop ESs addressing questions related to these areas. The frequency of anastomotic leak, hemorrhage, and wound complication is variable. September 2022: Vol. RCT with minor limitations affecting confidence in, or applicability of, the results. Weak recommendationThere is at least moderate certainty based on evidence that there is a small net benefit. On November 1, 2022, we hosted an online RNAi roundtable to review Alnylams CNS delivery platform and ALN-APP, an investigational RNAi therapeutic in development for Alzheimers Disease and cerebral amyloid angiopathy. Hlavn v okol Prahy v Odolen Vod, Svmyslicch, Husinci, Hoticch, Lbeznicch, Lobkovicch u Neratovic nebo Pedboji. Almonds vs complex carbohydrates in a weight reduction program. It does not necessarily reflect relationships with industry at the time of publication. Perioperative (30 day) and longer-term (>30 days) complications after bariatric surgery vary by procedure and patient-derived risk factors. Findings In this pooled analysis of the Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure (DAPA-HF) and Dapagliflozin Evaluation to Improve the Lives of Patients With Preserved Annual medical spending attributable to obesity: payer-and service-specific estimates. Increased physical activity: Comprehensive lifestyle intervention programs typically prescribe increased aerobic physical activity (such as brisk walking) for 150 min/wk (equal to 30 min/d most days of the week). Human Factors: The Journal of the Human Factors and Ergonomics Society publishes peer-reviewed scientific studies in human factors/ergonomics that present theoretical and practical advances concerning the relationship between people and technologies, tools, environments, and systems.Papers published in Human Factors leverage fundamental News Editor, theheart.org | Medscape CardiologyDisclosure: Steve Stiles has disclosed no relevant financial relationships. Shalom Jacobovitz, Chief Executive Officer, William J. Oetgen, MD, MBA, FACC, Executive Vice President, Science, Education & Quality, Charlene May, Senior Director, Science and Clinical Policy, American College of Cardiology/American Heart Association, Lisa Bradfield, CAE, Director, Science and Clinical Policy, Ezaldeen Ramadhan III, Team Leader, Science and Clinical Policy, Mariell Jessup, MD, FACC, FAHA, President, Rose Marie Robertson, MD, FAHA, Chief Science Officer, Gayle R. Whitman, PhD, RN, FAHA, FAAN, Senior Vice President, Office of Science Operations, Marco Di Buono, PhD, Vice President of Science and Research, Jody Hundley, Production Manager, Scientific Publications, Office of Science Operations, National Heart, Lung, and Blood Institute. You are now being directed to another Alnylam website that contains information about specific treatment(s). In 2005, the NHLBI initiated the process to update the overweight/obesity guidelines and convened stakeholder groups to provide input on what should be the next-generation guideline development process. Mediators of weight loss and weight loss maintenance in middle-aged women. To purchase additional reprints, call 843-216-2533 or e-mail [emailprotected]. Because of resource and time constraints, CQ1 was restricted to systematic reviews and meta-analyses published only between January 2000 and October 2011. All rights reserved. Please use this form to submit your questions or comments on how to make this article more useful to clinicians. Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies. WebThe HFSA Annual Scientific Meeting 2023 is where heart failure teams gather! In a few cases, lay persons were used as trained interventionists; they received instruction in weight management protocols (designed by health professionals) in programs that have been validated in high-quality trials published in peer-reviewed journals. The material on this site is for informational purposes only, and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Characteristics of Lifestyle Intervention Delivery That May Affect Weight Loss or Weight Loss Maintenance: On-Site Versus Electronically Delivered Interventions S124, 3.5.3.1. BVA-Guided Treatment Improves Hospital LOS & Outcomes. And the HFSA is also launching a HF certification specifically for advanced practice providers in the next few months, according to Shannon Cornell, A-NP, of Medical University of South Carolina in Charleston. Although the present analysis found this not to be true in contemporary practice, Itoh cautioned that it remains uncertain whether LAA occlusion makes anticoagulation management easier after LVAD surgery, particularly for people needing periprocedural discontinuation due to another operation, those predisposed to bleeding issues, and those nonadherent to anticoagulation. Welcome to Capella, Alnylams destination for updates on our work translating the breakthrough discovery of RNA interference (RNAi) into an innovative new class of medicines. A formal peer review process was initially completed under the auspices of the NHLBI and included 10 expert reviewers and representatives from multiple federal agencies. 03 Oct 2022 BioCardia Presents Positive CardiAMP Cell Therapy Heart Failure Trial Two-Year Data at HFSA Annual Meeting . ES9c (Effect of Intervention Intensity). *In some cases, other evidence, such as large all-or-none case series (eg, jumping from airplanes or tall structures), can represent high- or moderate-quality evidence. The Academy of Nutrition and Dietetics affirms the value of this guideline. Ad libitum approaches, in which a formal energy deficit target is not prescribed, but lower calorie intake is achieved by restriction or elimination of particular food groups or provision of prescribed foods. Opens in a new tab or window . Share cases and questions with Physicians on Medscape Consult. A total of 10 studies (12 articles) met the inclusion criteria, were rated as good or fair quality, and are included in the summary table.141,142,144,148,151,155,156,159,161,168,169,172 The studies were required to have a comparator group but not necessarily a nonsurgical comparator, as well as outcomes of specific bariatric operative procedures. Now available OnDemand! The morbidity and mortality associated with overweight and obesity in adulthood: a systematic review. Featured Announcements. ES3. NHLBI indicates National Heart, Lung, and Blood Institute; and RCT, randomized controlled trial. Characteristics of Lifestyle Intervention Delivery That May Affect Weight Loss or Weight Loss Maintenance: Individual Versus Group Treatment S124, 3.4.11. ES9a (Moderate-Intensity Interventions). Expert Panel members also played a key role in examining the evidence tables and summary tables to be certain the data from each article were accurately displayed. WebDecember 2022: Vol. Whatever the mechanism of benefit from dapagliflozin (Farxiga) in patients with heart failure (HF), the drug and potentially also other sodium-glucose cotransporter 2 (SGLT2) inhibitors its blood pressure (BP) lowering effects aren't likely to contribute much. On the basis of studies conducted in settings where all food is provided to deliver increased protein (25% of total calories) either as part of caloric restriction or with ad libitum energy consumption, there is insufficient evidence to inform recommendations for weight loss interventions in free-living overweight or obese individuals. *In most cases, the strength of the recommendation should be closely aligned with the quality of the evidence; however, under some circumstances, there may be valid reasons for making recommendations that are not closely aligned with the quality of the evidence (eg, strong recommendation when the evidence quality is moderate, such as smoking cessation to reduce CVD risk or ordering an ECG as part of the initial diagnostic work-up for a patient presenting with possible MI). Preventing weight gain: one-year results of a randomized lifestyle intervention. You will receive email when new content is published. When laparoscopic sleeve gastrectomy is performed by an experienced surgeon: There is insufficient evidence to establish the incidence of perioperative and longer-term complications. The mortality rate for BPD was reported by 2 of the 3 included studies. He cited a proposed pathway in which interested trainees pass through internal medicine residency and general cardiology fellowship before reaching AHFTC fellowship embedding cardiac critical care. 2022 ACC/AHA/HFSA Heart Failure Guideline for the Management of Heart Failure. We are developing cellular and cell-derived therapeutics for the treatment of cardiovascular and pulmonary diseasesto improve the lives of patients from unmet medical needs. Chronic Disease Management Model for Primary Care of Patients With Overweight and ObesityTreatment Algorithm S108, 3.1.1. WebHaving FOMO from #HFSA2022? 2014;129(suppl 2):S102S138. For each CQ, the Expert Panel summarized recommendations for future research. What are the predictors associated with complications? Among overweight and obese adults, what is the efficacy/effectiveness of a comprehensive lifestyle intervention program (ie, comprised of diet, physical activity, and behavior therapy) in facilitating weight loss or maintenance of lost weight? The live portion of the 2022 Virtual Annual Meeting has concluded. Weight losses after BPD, gastric bypass, and sleeve gastrectomy are similar. To review the NHLBI and ACC/AHAs current comprehensive policies for managing relationships with industry and other entities, please refer to http://www.nhlbi.nih.gov/guidelines/cvd_adult/coi-rwi_policy.htm and http://www.cardiosource.org/Science-And-Quality/Practice-Guidelines-and-Quality-Standards/Relationships-With-Industry-Policy.aspx. They also summarize knowledge on the best diets for weight loss, the efficacy and effectiveness of comprehensive lifestyle interventions on weight loss and weight loss maintenance, and the benefits and risks of bariatric surgery. To comment please, Comments on Medscape are moderated and should be professional in tone and on topic. Time to first HF hospitalization was reduced with SNB in both a control group (no SNB, 400.97 days: SNB, 257.11 days) and the BNP-guided group (no SNB, 409.56 days; SNB, 289.99 days). Compared with placebo, the addition of orlistat to lifestyle intervention in overweight and obese adults results in an average 3 kg greater weight loss together with an 8 to 12 mg/dL reduction in LDL-C, a 1 mg/dL reduction in HDL-C, and variable changes in triglycerides. Complications: What are the short-term (<30 days) and long-term (30 days) complications of the following bariatric surgical procedures? Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes mellitus: four-year results of the Look AHEAD trial. The NHLBI, in cooperation with the National Institute of Diabetes and Digestive and Kidney Diseases, released the 1998 Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in AdultsThe Evidence Report11 as a systematic review of the published scientific literature found in MEDLINE from January 1980 to September 1997 on important topics reviewed by the Expert Panel. In overweight and obese adults, there are no differences in weight loss at 6 months with instructions to consume a carbohydrate-restricted diet (20 g/d for up to 3 months, followed by increasing levels of carbohydrate intake up to a point at which weight loss plateaus) in comparison with instruction to consume a calorie-restricted, low-fat diet. Opens in a new tab or window, Visit us on LinkedIn. Relationships in this table are modest unless otherwise noted. Opens in a new tab or window (HFSA) annual meeting. by Nicole Lou, Senior Staff Writer, MedPage Today October 5, 2022 Share on Facebook. Nevertheless, high-quality literature that addresses these issues could exist. By day 16 after randomization, first and sustained statistical significance was achieved for worsening HF events (HR, 0.45). Of the 2317 citations identified through the database search, 811 citations were automatically excluded, and the titles and abstracts of the 1515 remaining citations were screened against the I/E criteria for each of the 3 components (efficacy, predictors, and complications) independently by 2 reviewers, which resulted in 1062 publications being excluded. The quality (internal validity) of these 42 publications was assessed using the quality assessment tool developed to assess systematic reviews, meta-analyses, or RCTs. NATIONAL HARBOR, Md. Exhibitor Immunomedics 02-20. Send comments and news tips to news@medscape.net. These policies were in effect when this effort began in 2008 and throughout the writing process and voting on recommendations, until the process was transferred to ACC/AHA in 2013. Published online October 2, 2022. Twitter. Check out our web page for a full conference listing and registration offerings! WebHFSA Annual Scientific Meeting 2023; OnDemand Education. A total of 5 studies (17 articles) met the criteria for determining the efficacy of bariatric surgery for weight loss and the impact on obesity-related comorbidities, were rated as good or fair quality, and are included in the summary table. For now, Katz urged stakeholders to engage professional societies like the American College of Cardiology to develop new training pathways and determine what is necessary for the future of cardiac critical care. Facebook. Click the topic below to receive emails when new articles are available. Effect of energy-reduced diets high in dairy products and fiber on weight loss in obese adults. Expert opinion (There is insufficient evidence or evidence is unclear or conflicting, but this is what the Work Group recommends.)Net benefit is unclear. Read the press release Maurer, et al. Of these, 14 publications were rated as poor quality. Of these, 74 publications were excluded because they were rated as poor quality; of those 74 publications, 43 studies were rated poor because of the intention-to-treat and attrition rates. Lactoovovegetarianstyle diet with prescribed energy restriction. The 2022 ACC/AHA/HFSA Guideline for the Management of Heart Failure increases the focus on preventing HF, updates treatment strategies for people with symptomatic heart failure to include SGLT-2 inhibitor (SGLT2i) medicines and emphasizes care coordination with a heart failure specialty team. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Learners can view recorded presentations to enhance their The findings "reinforce the clinical benefits of SGLT2 inhibitors in patients with heart failure across the full spectrum of ejection fractions and large range of systolic blood pressures," said GreggC. Fonarow, MD, University of California Los Angeles Medical Center, who was not part of the DELIVER analysis. After 1 month, mean systolic BP had fallen by 1.8 mmHg (P < .001) in patients who had been randomly assigned to dapagliflozin vs placebo. Check for Hotel Rooms and Registration process. More research is needed to inform future guidelines focusing on improvements in efficiency and efficacy, optimizing delivery and dissemination, and targeting special populations. Although lifestyle intervention is the mainstay of all weight management treatment, there is increasing recognition of the need for adjunctive treatments for patients with obesity who are at high medical risk and who are unable to achieve or maintain sufficient weight loss to improve their health. "We need to rebrand ourselvesWe're not just [ventricular assist device] and transplant physicians," said Kataria. What are the long-term effects of the following surgical procedures on weight loss, weight loss maintenance, cardiovascular risk factors, related comorbidities, and mortality? 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Today October 5, 2022 share on Facebook, MD, hfsa annual meeting 2022 of California Los Angeles Center! 2014 ; 129 ( suppl 2 ): S102S138 by an experienced surgeon There! On how to make this article more useful to clinicians Staff Writer, MedPage Today October 5, share... Nebo Pedboji 30 days ) complications of the 3 included studies for worsening events! Factors associated with long-term success no significant effect on survival and stroke LAA... Practice guidelines for prevention associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of prospective! Compared with usual care is What the Work Group recommends in this table are modest unless otherwise noted randomized Intervention... Reason, the Expert Panel summarized recommendations for future research pohybovali jsme ve... To clinicians by an experienced surgeon: There is insufficient evidence or evidence is unclear or conflicting but... 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