Patients hormone receptor (estrogen receptor [ER] and progesterone receptor [PR]) status must be known and will be determined by local testing. And Im one of the lucky ones: my triple negative breast cancer was diagnosed in time to be treatable. Knowing what to expect before, during, and after chemotherapy treatment can be a significant help in managing the treatment. Then, when I was 30 my best friend Erin died from breast cancer. These skin problems usually develop slowly over days to weeks after your treatment starts. Last medically reviewed on June 15, 2021 Cancer / Oncology To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. Multiple lesions that appear part of the same index tumor do not require additional biopsy/HER2 testing. For general information, Learn About Clinical Studies. WebThe OnePoll* survey, polled 500 people currently living with cancer. (Exploratory Clinical Objective) II. Sadly, Kimberley experienced the sorrow of cancer when she was young, as her mum passed away with breast cancer the year after we met, aged 18. WebDon't get scammed this holiday season. Over half (55%) of those surveyed also said they think they will struggle to pay for food this winter and two thirds (67%) think heating Events include distant recurrence and second primary non-breast invasive cancer (other than squamous or basal cell skin cancer). The second session I almost went into anaphylacus which really terrified. Baseline imaging of the ipsilateral axilla by ultrasound or breast MRI is mandatory. Oct 14 WebScottish perspective on news, sport, business, lifestyle, food and drink and more, from Scotland's national newspaper, The Scotsman. Following treatment which included a lumpectomy and radiotherapy, all was fine. Had very bad side effects. Choosing to participate in a study is an important personal decision. In China the breast cancer rate was one in 100,000 compared to one in ten here. WebThis trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Following a bumpy launch week that saw frequent server trouble and bloated player queues, Blizzard has announced that over 25 million Overwatch 2 players have logged on in its first 10 days. until the end of trastuzumab and pertuzumab [HP] therapy). The European Journal of Cancer (EJC) integrates preclinical, digital, translational, and clinical research in cancer, from epidemiology, carcinogenesis and biology through to innovations in cancer treatment and patient care.The journal publishes original research, reviews, previews, editorial comments and correspondence. A struggling dad-of-eight whose wife has cancer is using food banks and plans to skip hot meals to ensure his family is fed.. (Exploratory Clinical Objective) V. To determine axillary pCR rates as a function of the burden of disease at presentation as determined on pre-treatment ultrasound (US) and the axillary staging technique (SLNB plus ensuring removal of clipped node versus ALND). The analysis will be descriptive and there will be no statistical test. Knowing what to expect before, during, and after chemotherapy treatment can be a significant help in managing the treatment. In China the breast cancer rate was one in 100,000 compared to one in ten here. Events include recurrence of ipsilateral invasive breast tumor, recurrence of locoregional invasive breast tumor, and distant recurrence. I was high risk. Patents must have a left ventricular ejection fraction (LVEF) within normal institutional parameters (or > 50%). View this study on Beta.ClinicalTrials.gov, AKPAMC.OncologyResearchSupport@providence.org, ResearchInstituteInquiries@CommonSpirit.org, ContactUsCancerCenter@TuftsMedicalCenter.org, OncologyClinicalTrialsFargo@sanfordhealth.org, CancCtrOncologyClinicalResearch@unchealth.unc.edu, oncology.clinical.trials@marshfieldresearch.org, U.S. Department of Health and Human Services. To determine the false negative rate (FNR) of limited staging procedures (defined as sentinel lymph node biopsy [SLNB] plus removal of clipped node) in patients who undergo such procedures with a planned axillary lymph node dissection (ALND). POST-OPERATIVE/ADJUVANT THERAPY: Patients are assigned to 1 of 2 arms. (Clinical Trial), (CompassHER2-pCR): Preoperative THP and Postoperative HP in Patients Who Achieve a Pathologic Complete Response, Experimental: Arm B (residual invasive disease after surgery), 18 Years and older (Adult, Older Adult), University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States, 35233, Contact: Site Public Contact 205-934-0220, Anchorage Associates in Radiation Medicine, Contact: Site Public Contact 907-212-6871, Contact: Site Public Contact 907-458-3043, Contact: Site Public Contact 702-384-0013, Contact: Site Public Contact 602-406-0777, Principal Investigator: Richard L. Deming, University of Arizona Cancer Center-Orange Grove Campus, Contact: Site Public Contact 520-694-8900, Principal Investigator: Jennifer M. Segar, Banner University Medical Center - Tucson, University of Arizona Cancer Center-North Campus, Contact: Site Public Contact 800-327-2873, Fort Smith, Arkansas, United States, 72903, Contact: Site Public Contact 800-378-9373, CHI Saint Vincent Cancer Center Hot Springs, Hot Springs, Arkansas, United States, 71913, NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro, Jonesboro, Arkansas, United States, 72401, Contact: Site Public Contact 870-936-7066, Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande, California, United States, 93420, Contact: Site Public Contact 805-219-4673, Contact: Site Public Contact 415-209-2683, Principal Investigator: Kristie A. Bobolis, Sutter Cancer Centers Radiation Oncology Services-Auburn, Alta Bates Summit Medical Center-Herrick Campus, Berkeley, California, United States, 94704, Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank, California, United States, 91505, Contact: Site Public Contact 818-847-4793, Burlingame, California, United States, 94010, Sutter Cancer Centers Radiation Oncology Services-Cameron Park, Cameron Park, California, United States, 95682, Castro Valley, California, United States, 94546, Contact: Site Public Contact 925-875-1677, Emeryville, California, United States, 94608, Contact: Site Public Contact 510-835-9900, Contact: Site Public Contact 510-629-6682, Fremont, California, United States, 94538, Contact: Site Public Contact 510-745-6433, Principal Investigator: Bogdan S. Eftimie, Huntington Beach, California, United States, 92648, Los Angeles, California, United States, 90033, Martinez, California, United States, 94553-3156, Contact: Site Public Contact 925-957-5400, Marysville, California, United States, 95901, Contact: Site Public Contact 530-749-4400, Modesto, California, United States, 95355, Palo Alto Medical Foundation-Camino Division, Mountain View, California, United States, 94040, Palo Alto Medical Foundation-Gynecologic Oncology, USC Norris Oncology/Hematology-Newport Beach, Newport Beach, California, United States, 92663, Alta Bates Summit Medical Center - Summit Campus, Oakland, California, United States, 94609, Contact: Site Public Contact 510-465-2242, Contact: Site Public Contact 714-734-6220, Palm Springs, California, United States, 92262, Contact: Site Public Contact 760-416-4730, Palo Alto, California, United States, 94301, Palo Alto, California, United States, 94304, Contact: Site Public Contact 650-498-7061, Pasadena, California, United States, 91105, Sutter Cancer Centers Radiation Oncology Services-Roseville, Roseville, California, United States, 95661, Sacramento, California, United States, 95816, Saint Helena, California, United States, 94574, Contact: Site Public Contact 707-967-3698, Salinas, California, United States, 93901, Contact: Site Public Contact 831-759-1838, Zuckerberg San Francisco General Hospital, San Francisco, California, United States, 94110, Contact: Site Public Contact 415-476-4082, California Pacific Medical Center-Pacific Campus, San Francisco, California, United States, 94115, San Jose, California, United States, 95124, Pacific Central Coast Health Center-San Luis Obispo, San Luis Obispo, California, United States, 93401, Santa Cruz, California, United States, 95065, Mission Hope Medical Oncology - Santa Maria, Santa Maria, California, United States, 93444, Santa Rosa, California, United States, 95403, Sunnyvale, California, United States, 94086, Gene Upshaw Memorial Tahoe Forest Cancer Center, Truckee, California, United States, 96161, Contact: Site Public Contact 530-582-6450, Sutter Cancer Centers Radiation Oncology Services-Vacaville, Vacaville, California, United States, 95687, Sutter Solano Medical Center/Cancer Center, Vallejo, California, United States, 94589, Walnut Creek, California, United States, 94597, Contact: Site Public Contact 510-465-8016, Contact: Site Public Contact 303-777-2663, Contact: Site Public Contact 720-848-0650, Principal Investigator: Virginia F. Borges, Rocky Mountain Cancer Centers - Centennial, Centennial, Colorado, United States, 80112, Colorado Springs, Colorado, United States, 80907, Contact: Site Public Contact 719-776-6550, Colorado Springs, Colorado, United States, 80909, Contact: Site Public Contact 719-365-2406, Colorado Springs, Colorado, United States, 80920, Contact: Site Public Contact 719-364-6700, Colorado Springs, Colorado, United States, 80923, Presbyterian - Saint Lukes Medical Center - Health One, Mountain Blue Cancer Care Center - Swedish, Englewood, Colorado, United States, 80113, Fort Collins, Colorado, United States, 80524, Contact: Site Public Contact 970-297-6150, Fort Collins, Colorado, United States, 80528, Grand Junction, Colorado, United States, 81505, Contact: Site Public Contact 970-644-4460, Principal Investigator: Kristina Goutsouliak, Highlands Ranch, Colorado, United States, 80129, Littleton, Colorado, United States, 80120, Littleton, Colorado, United States, 80122, Lone Tree, Colorado, United States, 80124, Contact: Site Public Contact 970-203-7083, Hartford HealthCare - Saint Vincent's Medical Center, Bridgeport, Connecticut, United States, 06606, Contact: Site Public Contact 860-972-4700, Principal Investigator: Rajani P. Nadkarni, Contact: Site Public Contact 203-785-5702, Smilow Cancer Hospital Care Center-Fairfield, Fairfield, Connecticut, United States, 06824, Smilow Cancer Hospital Care Center at Glastonbury, Glastonbury, Connecticut, United States, 06033, Smilow Cancer Hospital Care Center at Greenwich, Greenwich, Connecticut, United States, 06830, Smilow Cancer Hospital Care Center - Guiford, Guilford, Connecticut, United States, 06437, Hartford, Connecticut, United States, 06102, Contact: Site Public Contact 860-545-5363, Smilow Cancer Hospital Care Center at Saint Francis, Hartford, Connecticut, United States, 06105, Meriden, Connecticut, United States, 06451, Contact: Site Public Contact 866-662-5678, New Britain, Connecticut, United States, 06050, Contact: Site Public Contact 860-224-5660, Smilow Cancer Center/Yale-New Haven Hospital, New Haven, Connecticut, United States, 06510, New Haven, Connecticut, United States, 06520, Yale-New Haven Hospital North Haven Medical Center, North Haven, Connecticut, United States, 06473, Smilow Cancer Hospital-Orange Care Center, Orange, Connecticut, United States, 06477, Smilow Cancer Hospital Care Center at Long Ridge, Stamford, Connecticut, United States, 06902, Stamford, Connecticut, United States, 06904, Contact: Site Public Contact 203-323-8944, Smilow Cancer Hospital-Torrington Care Center, Torrington, Connecticut, United States, 06790, Smilow Cancer Hospital Care Center-Trumbull, Trumbull, Connecticut, United States, 06611, Smilow Cancer Hospital-Waterbury Care Center, Waterbury, Connecticut, United States, 06708, Smilow Cancer Hospital Care Center - Waterford, Waterford, Connecticut, United States, 06385, Frankford, Delaware, United States, 19945, Contact: Site Public Contact 302-645-3100, Principal Investigator: Gregory A. Chemotherapy was effective in shrinking the tumours and, after mastectomy surgery and radiotherapy, followed by a bit more chemo for good measure, Im out the Patients with the following cancers are eligible if diagnosed and treated within the past 5 years: cervical cancer in situ, basal cell or squamous cell carcinoma of the skin, and localized papillary or follicular thyroid cancer who have completed recommended treatment including surgery. To evaluate the associations between plasma tumor cell-free deoxyribonucleic acid (DNA) (cfDNA) tumor-specific mutations (baseline and after therapy) with pathologic response and long-term outcomes (including RFS, EFS, IDFS, DDFS, DRFS, RFI, OS, and breast cancer-specific survival). Why Should I Register and Submit Results? Many online companies offer wigs and caps as well. That means the impact could spread far beyond the agencys payday lending rule. November 25 Grey wolves infected with this parasite more likely to become pack leaders That means the impact could spread far beyond the agencys payday lending rule. Sadly, Kimberley experienced the sorrow of cancer when she was young, as her mum passed away with breast cancer the year after we met, aged 18. Survival curve estimated using Kaplan-Meier method in the overall analysis population and by pretreatment clinical stage and estrogen receptor (ER) status. The glue was slipping quite substantially," she admits. 80% of people with cancer also said they are worried about the cost of travel to their hospital appointments with over a third (34%) saying they worry very much. WebHearst Television participates in various affiliate marketing programs, which means we may get paid commissions on editorially chosen products purchased through our links to retailer sites. The tumor must have either HER2 IHC result of 3+ or HER2/CEP17 ratio > 2 with > 4.0 HER2 signals per cell by ISH. She discusses with Helen Saul a collaborative project involving the Belgium Cancer Registry and the College for Physicians in Radiation Oncology. News Now clips, interviews, movie premiers, exclusives, and more! to chemotherapy and that it would return when my treatment finished. My aunt died from complications due to breast cancer about 25 years ago. Information provided by (Responsible Party): Eastern Cooperative Oncology Group ( ECOG-ACRIN Cancer Research Group ). To evaluate safety and tolerability for all patients during the pre-operative phase and for patients who attain pCR and de-escalate therapy (Arm A) until the completion of post-surgery protocol assigned therapy (i.e. Over half (55%) of those surveyed also said they think they will struggle to pay for food this winter and two thirds (67%) think heating WebRead latest breaking news, updates, and headlines. To determine 3-year IDFS (invasive disease-free survival), DDFS (distant disease-free survival), DRFS (distant relapse-free survival), RFI (recurrence-free interval), OS (overall survival) and breast cancer-specific survival in patients who achieve pCR (and by pretreatment clinical stage). When Anna was diagnosed with breast cancer last year, she expected the worst from her treatment. A man who found the body of his neighbour who had vanished for eight days has described the horror of finding him on top of his house. This trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. A clip must be placed in the involved axillary lymph node. Plasma total cell-free DNA (cfDNA) is a surrogate biomarker for tumour burden and a prognostic biomarker for survival in metastatic melanoma patients. WebWe do know that some of the side effects from standard or traditional chemo drugs can last a lifetime, such as when the drug causes long-term damage to the heart, lungs, kidneys, or reproductive organs. Patients also receive trastuzumab IV on day 1 or days 1, 8, and 15, and pertuzumab IV on day 1. I. The EJC is the (Exploratory Correlative Objective) VII. WATCH: Many breast cancer patients face memory problems during chemo "The mum that holds everything together wasn't holding everything together. (Secondary Clinical Objective) III. Then, when I was 30 my best friend Erin died from breast cancer. My aunt died from complications due to breast cancer about 25 years ago. The second session I almost went into anaphylacus which really terrified. Please remove one or more studies before adding more. In addition, about 2,400 men are diagnosed with breast cancer each year and some 500 men die from it annually, CDC data shows. I cant rally myself to do anything. A struggling dad-of-eight whose wife has cancer is using food banks and plans to skip hot meals to ensure his family is fed.. WebHearst Television participates in various affiliate marketing programs, which means we may get paid commissions on editorially chosen products purchased through our links to retailer sites. Patients must have AJCC 8th Edition stage II or IIIa according to anatomic staging table at diagnosis. Gina Atkins from Cardiff was first diagnosed with Breast cancer in 2019. To determine 3-year EFS (event-free survival) in all patients from time of study registration. Trastuzumab and pertuzumab are both a form of "targeted therapy" because they work by attaching themselves to specific molecules (receptors) on the surface of tumor cells, known as HER2 receptors. Multiple lesions that appear part of the same index tumor do not require additional biopsy/HER2 testing. The American Cancer Society offers a non-profit service for women called Tender Loving Care, that offers a catalog featuring a variety of products. WebRead latest breaking news, updates, and headlines. WebRead latest breaking news, updates, and headlines. (Secondary Clinical Objective) IV. active) cardiovascular disease: cerebrovascular accident/stroke or myocardial infarction within 6 months prior to registration, unstable angina, congestive heart failure (CHF) or serious cardiac arrhythmia requiring medication and other concurrent serious diseases that may interfere with planned treatment, All patients of childbearing potential is anyone, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: 1) has achieved menarche at some point, 2) has not undergone a hysterectomy or bilateral oophorectomy; or 3) has not been naturally postmenopausal for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months). POST-OPERATIVE.ADJUVANT THERAPY: Patients with pCR after surgery receive trastuzumab and pertuzumab IV on day 1. WebScottish perspective on news, sport, business, lifestyle, food and drink and more, from Scotland's national newspaper, The Scotsman. Get information on latest national and international events & more. However, with support from family and friends, she was able to get through it with positivity. Get information on latest national and international events & more. WebMSN Health is a leading fitness, wellness, and nutrition resource, with medically reviewed guides, health management tools, and content from respected sources. News Now clips, interviews, movie premiers, exclusives, and more! Here's what you need to look out for Patient must be willing and able to sign informed consent, Leukocytes >= 3,000/mcL (obtained =< 28 days prior to protocol registration), Absolute neutrophil count >= 1,500/mcL (obtained =< 28 days prior to protocol registration), Platelets >= 100,000/mcL (obtained =< 28 days prior to protocol registration), Total bilirubin =< 1.5 x institutional upper limit of normal (ULN) (obtained =< 28 days prior to protocol registration), Aspartate aminotransferase (AST) (serum glutamic-oxaloacetic transaminase [SGOT])/alanine aminotransferase (ALT) (serum glutamate pyruvate transaminase [SGPT]) =< 2.5 x institutional ULN (obtained =< 28 days prior to protocol registration), Creatinine =< 1.5 x institutional ULN (obtained =< 28 days prior to protocol registration), Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial, For patients with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy, if indicated, Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. I ended up in hospital with diviticulitis after the first session. You will then receive an email that contains a secure link for resetting your password, If the address matches a valid account an email will be sent to __email__ with instructions for resetting your password. Check with your cancer center to see what resources are available in your area. Tumors with HER2/CEP17 ISH ratio < 2 are ineligible, even if HER2 copy number is > 6, unless HER2 IHC result is 3+. He tells Helen Saul that if trends continue, never-smokers diagnosed with lung cancer could outnumber smokers within the next 10 years. WATCH: Many breast cancer patients face memory problems during chemo "The mum that holds everything together wasn't holding everything together. The glue was slipping quite substantially," she admits. Comprehensive breast and axillary imaging must be performed within 42 days of registration (i.e. However, even if biopsy is not deemed necessary, consideration should be given to placing a clip in any lesion that is 1 cm or further from the primary tumor to ensure that all tumor is removed at surgery AND that the pathologist can locate all primary sites of tumor to assess pathologic response at surgery. Charlotte Crosby has given fans an update on her mother Letitia's cancer battle, saying her parent is 'doing amazing'. Over half (55%) of those surveyed also said they think they will struggle to pay for food this winter and two thirds (67%) think heating His wife was only 35 and breast feeding our grandson at 14 months old when she started treatment with a double mastectomy then chemo and then radiation. The EJC is the Part 2: Treatment - Update 2022. The European Journal of Cancer (EJC) integrates preclinical, digital, translational, and clinical research in cancer, from epidemiology, carcinogenesis and biology through to innovations in cancer treatment and patient care.The journal publishes original research, reviews, previews, editorial comments and correspondence. He tells Helen Saul that the new results could improve the management of treatment. Amy Lysyczyn: Mines a little bit unique. (Secondary Clinical Objective) II. Treatment repeats every 21 days for up to 4 cycles in the absence of disease progression or unacceptable toxicity. Simon Pernot (Hpital Europen Georges-Pompidou, Paris France) says that circulating tumour cells may be a valuable prognostic biomarker in advanced gastric cancer. The analysis will be descriptive and there will be no statistical test. My aunt died from complications due to breast cancer about 25 years ago. Patients with any other cancers within the last 5 years are ineligible. Nobody tells you how hard the months following cancer treatment are. The incidence of adverse events leading to discontinuation of protocol therapy will be summarized and listed as well. When these drugs attach to HER2 receptors, the signals that tell the cells to grow are blocked and the tumor cell may be marked for destruction by the body's immune system. Following treatment which included a lumpectomy and radiotherapy, all was fine. A struggling dad-of-eight whose wife has cancer is using food banks and plans to skip hot meals to ensure his family is fed.. However, with support from family and friends, she was able to get through it with positivity. My hair thinned on the first chemo regime, but this last regime of chemo I have kept a full head of hair. Oct 14 Patients may also receive additional standard of care chemotherapy, as well as hormone therapy if appropriate. Following a bumpy launch week that saw frequent server trouble and bloated player queues, Blizzard has announced that over 25 million Overwatch 2 players have logged on in its first 10 days. ClinicalTrials.gov Identifier: NCT04266249, Interventional Patients must not have > grade 1 peripheral neuropathy of any etiology. new bone pain) or abnormal physical exam findings (National Comprehensive Cancer Network [NCCN] guidelines version [V]1.2019), Patient must not have T4 and/or N3 disease, including inflammatory breast cancer, Patient must not have any prior treatment for the current breast cancer, including surgery, chemotherapy, hormonal therapy, radiation or experimental therapy, Patients must not have > grade 1 peripheral neuropathy of any etiology, Patient must not have a concurrent serious medical condition that would preclude completion of study therapy. For subjects with axillary lymph node(s) suspicious on clinical exam or imaging, patient must be willing to have a needle aspiration or core biopsy to determine the presence of metastatic disease in the lymph nodes. Six people were gunned down two days before Thanksgiving at a Walmart in Chesapeake, Virginia. It made me very hypervigilant and ironically, about five months after she died, I found my first mass and lump. Will be graded using the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) version (v)5.0. Since breast cancer is more commonly found in women ages 40 and older, medical professionals and organizations recommend routine breast cancer screenings for middle-aged and senior women. Patients may also undergo standard of care radiation therapy and receive hormone therapy if appropriate. Patients may also receive additional standard of care chemotherapy, as well as hormone therapy if appropriate. The American Cancer Society offers a non-profit service for women called Tender Loving Care, that offers a catalog featuring a variety of products. The TV presenter and property expert, 50, revealed last month that she had been diagnosed with breast cancer and has since undergone at least one round of chemotherapy. To evaluate the associations between tumor infiltrating lymphocytes (TILs) and immune activation gene signatures in the baseline tumor with pathologic response and long-term outcomes (including RFS, EFS, IDFS, DDFS, DRFS, RFI, OS and breast cancer-specific survival). To determine 3-year RFS, IDFS (invasive disease-free survival), DDFS (distant disease-free survival), DRFS (distant relapse-free survival), RFI (recurrence-free interval), OS (overall survival) and breast cancer-specific survival in patients who do not achieve pCR (and by pretreatment clinical stage). Get the latest health news, diet & fitness information, medical research, health care trends and health issues that affect you and your family on ABCNews.com The EJC is the Since breast cancer is more commonly found in women ages 40 and older, medical professionals and organizations recommend routine breast cancer screenings for middle-aged and senior women. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Had very bad side effects. Patient must not have a history of any prior (ipsilateral or contralateral) invasive breast cancer, Patient must not have prior ipsilateral ductal breast carcinoma in situ (DCIS). To evaluate the association of estrogen receptor (ER) status in the untreated primary tumor with pathologic response and with long-term survival outcomes (including RFS, EFS, IDFS, DDFS, DRFS, RFI, OS, and breast cancer-specific survival). Nobody tells you how hard the months following cancer treatment are. WebThe OnePoll* survey, polled 500 people currently living with cancer. Then, when I was 30 my best friend Erin died from breast cancer. Six people were gunned down two days before Thanksgiving at a Walmart in Chesapeake, Virginia. Check with your cancer center to see what resources are available in your area. 80% of people with cancer also said they are worried about the cost of travel to their hospital appointments with over a third (34%) saying they worry very much. Survival curve estimated using Kaplan-Meier method in the overall analysis population and by pretreatment clinical stage and ER status. I cant rally myself to do anything. WebWe do know that some of the side effects from standard or traditional chemo drugs can last a lifetime, such as when the drug causes long-term damage to the heart, lungs, kidneys, or reproductive organs. WebWe do know that some of the side effects from standard or traditional chemo drugs can last a lifetime, such as when the drug causes long-term damage to the heart, lungs, kidneys, or reproductive organs. WebIn pre-Covid days, at a time before Leanne Smith, 29, moved from Aberdeen to Cambridge, she had already felt a lump in her breast, which luckily turned out to be benign. Greenwood method will be used to estimate the 95% confidence interval for 3-year rate. (Exploratory Correlative Objective). November 25 Grey wolves infected with this parasite more likely to become pack leaders WebHearst Television participates in various affiliate marketing programs, which means we may get paid commissions on editorially chosen products purchased through our links to retailer sites. (Exploratory Correlative Objective) VIII. A man who found the body of his neighbour who had vanished for eight days has described the horror of finding him on top of his house. Patients must have a bilateral mammogram and a diagnostic breast ultrasound [on the side of the cancer(s)] (with or without breast MRI) performed at screening. I was high risk. WebScottish perspective on news, sport, business, lifestyle, food and drink and more, from Scotland's national newspaper, The Scotsman. "The holding will call into question many other regulations that protect consumers with respect to credit cards, bank accounts, mortgage loans, debt collection, credit reports, and identity theft," tweeted Chris Peterson, a former enforcement attorney at the CFPB who is To determine the frequency of change in intrinsic subtype between pretreatment tumor specimen and residual disease at the time of surgery. The TV presenter and property expert, 50, revealed last month that she had been diagnosed with breast cancer and has since undergone at least one round of chemotherapy. Following a bumpy launch week that saw frequent server trouble and bloated player queues, Blizzard has announced that over 25 million Overwatch 2 players have logged on in its first 10 days. I had chemo 20 yrs ago for breast cancer and cant remember it being as bad as Im feeling with this latest chemo for bowel cancer. to chemotherapy and that it would return when my treatment finished. That means the impact could spread far beyond the agencys payday lending rule. To determine if 3-year recurrence-free survival (RFS) is greater than 92% among clinical stages II or IIIa patients with HER2-positive breast cancer who achieve pathologic complete response (pCR) (ypT0/is ypN0) after preoperative therapy with 12 weeks of a taxane, trastuzumab (or Food and Drug Administration [FDA] approved biosimilar) and pertuzumab (THP x 12). Knowing what to expect before, during, and after chemotherapy treatment can be a significant help in managing the treatment. "The holding will call into question many other regulations that protect consumers with respect to credit cards, bank accounts, mortgage loans, debt collection, credit reports, and identity theft," tweeted Chris Peterson, a former enforcement attorney at the CFPB who is WebSee hot celebrity videos, E! Studies a U.S. FDA-regulated Drug Product: Studies a U.S. FDA-regulated Device Product: Albumin-Stabilized Nanoparticle Paclitaxel, paclitaxel albumin-stabilized nanoparticle formulation, Herceptin Trastuzumab Biosimilar PF-05280014, Trastuzumab-MCC-DM1 Antibody-Drug Conjugate, Recurrence-free survival (RFS) [TimeFrame:Up to 3 years after end of treatment], Invasive disease-free survival (IDFS) [TimeFrame:Up to 3 years after the end of treatment], Distant disease-free survival (DDFS) [TimeFrame:Up to 3 years after the end of treatment], Distant relapse-free survival (DRFS) [TimeFrame:U to 3 years after the end of treatment], Recurrence-free interval (RFI) [TimeFrame:Up to 3 years after the end of treatment], Overall survival (OS) [TimeFrame:From date of surgery until the date of death from any cause, assessed up to 3 years after the end of treatment], Event-free survival (EFS) [TimeFrame:Up to 3 years after the end of treatment], Incidence of adverse events (AEs) [TimeFrame:Up to 1 week after cycle 4 (all patients) and/or up to cycle 13 post-surgery (Arm A only) (each cycle is 21 days)], Patients must have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1. Events include recurrence of ipsilateral invasive breast tumor, recurrence of locoregional invasive breast tumor, distant recurrence, contralateral invasive breast cancer, and second primary non-breast invasive cancer (other than squamous or basal cell skin cancer). Treatment repeats every 21 days for up to 13 cycles in the absence of disease progression or unacceptable toxicity. In addition, about 2,400 men are diagnosed with breast cancer each year and some 500 men die from it annually, CDC data shows. WATCH: Many breast cancer patients face memory problems during chemo "The mum that holds everything together wasn't holding everything together. per eligibility 3.1.5). I cant rally myself to do anything. Giving paclitaxel, trastuzumab, and pertuzumab may enable fewer chemotherapy drugs to be given without compromising patient outcomes compared to the usual treatment. WebJericho's Brandt Morgan beating back cancer on his road to QB-1 Jericho High School senior continues to receive chemo treatments as he leads his teammates on the gridiron. (Secondary Correlative Objective), I. Patient of childbearing potential and sexually active patients must use accepted and effective method(s) of contraception or to abstain from sexual intercourse for the duration of their participation in the study and for 7 months after the last dose of study treatment. Charlotte Crosby has given fans an update on her mother Letitia's cancer battle, saying her parent is 'doing amazing'. And Im one of the lucky ones: my triple negative breast cancer was diagnosed in time to be treatable. However, with support from family and friends, she was able to get through it with positivity. News Now clips, interviews, movie premiers, exclusives, and more! Part 1: Diagnostics: Update 2022, Maintenance olaparib plus bevacizumab in patients with newly diagnosed advanced high-grade ovarian cancer: Main analysis of second progression-free survival in the phase III PAOLA-1/ENGOT-ov25 trial, European consensus-based interdisciplinary guideline for melanoma. WebThis trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Patients with multiple ipsilateral invasive tumors are eligible as long as all tumors are HER2-positive, and at least one tumor focus meets eligibility criteria (per eligibility 3.1.5). An axillary ultrasound on the side of the cancer(s) is also required. I had chemo 20 yrs ago for breast cancer and cant remember it being as bad as Im feeling with this latest chemo for bowel cancer. (Exploratory Clinical Objective) VI. The TV presenter and property expert, 50, revealed last month that she had been diagnosed with breast cancer and has since undergone at least one round of chemotherapy. The incidence of deaths and treatment-emergent serious adverse events (defined as number of patients experiencing the AE divided by all treated patients) will be summarized using binominal proportions and binomial exact 95% confidence intervals. All patients of childbearing potential must have a blood test or urine study within 14 days prior to registration to rule out pregnancy. Gina Atkins from Cardiff was first diagnosed with Breast cancer in 2019. Patients must also not expect to conceive from the time of registration, while on study treatment, and until at least 7 months after the last dose of study treatment. Had very bad side effects. When Anna was diagnosed with breast cancer last year, she expected the worst from her treatment. Last medically reviewed on June 15, 2021 Cancer / Oncology To determine the association between residual cancer burden (RCB) and all described standardized definitions for efficacy end points (STEEP) criteria outcomes. For example, uncontrolled hypertension (systolic > 180 mm Hg and/or diastolic > 100 mm Hg) or clinically significant (i.e. to chemotherapy and that it would return when my treatment finished. Patient must have histologically confirmed HER2-positive primary invasive breast carcinoma, determined by local testing. The European Journal of Cancer (EJC) integrates preclinical, digital, translational, and clinical research in cancer, from epidemiology, carcinogenesis and biology through to innovations in cancer treatment and patient care.The journal publishes original research, reviews, previews, editorial comments and correspondence. Dynamic evaluation of circulating tumour cells in patients with advanced gastric and oesogastric junction adenocarcinoma: Prognostic value and early assessment of therapeutic effects, View all European Journal of Cancer Podcasts, We use cookies to help provide and enhance our service and tailor content. The second session I almost went into anaphylacus which really terrified. His wife was only 35 and breast feeding our grandson at 14 months old when she started treatment with a double mastectomy then chemo and then radiation. The American Cancer Society offers a non-profit service for women called Tender Loving Care, that offers a catalog featuring a variety of products. It made me very hypervigilant and ironically, about five months after she died, I found my first mass and lump. Talk with your doctor and family members or friends about deciding to join a study. (Secondary Correlative Objective) V. To evaluate the associations of detection of circulating tumor cells (CTCs) in the blood at baseline with pCR. Treatment repeats every 21 days for up to 4 cycles in the absence of disease progression or unacceptable toxicity. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04266249. WebSee hot celebrity videos, E! WebThe OnePoll* survey, polled 500 people currently living with cancer. To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Sadly, Kimberley experienced the sorrow of cancer when she was young, as her mum passed away with breast cancer the year after we met, aged 18. Gina Atkins from Cardiff was first diagnosed with Breast cancer in 2019. And Im one of the lucky ones: my triple negative breast cancer was diagnosed in time to be treatable. Amy Lysyczyn: Mines a little bit unique. Drugs used in chemotherapy, such as paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. SURGERY: Within 42 days after last dose of neoadjuvant therapy, patients undergo standard of care lumpectomy and/or mastectomy. Increasing frequency of non-smoking lung cancer: Presentation of patients with early disease to a tertiary institution in the UK. (Secondary Correlative Objective) VI. WebIn pre-Covid days, at a time before Leanne Smith, 29, moved from Aberdeen to Cambridge, she had already felt a lump in her breast, which luckily turned out to be benign. His wife was only 35 and breast feeding our grandson at 14 months old when she started treatment with a double mastectomy then chemo and then radiation. To evaluate the associations between DNA copy number, DNA mutations, ribonucleic acid (RNA) expression and protein expression in the baseline tumor and changes from baseline to post-THP therapy with pathologic response and long-term outcomes (including RFS, EFS, IDFS, DDFS, DRFS, RFI, OS, and breast cancer-specific survival). Six people were gunned down two days before Thanksgiving at a Walmart in Chesapeake, Virginia. Many online companies offer wigs and caps as well. My hair thinned on the first chemo regime, but this last regime of chemo I have kept a full head of hair. WebJericho's Brandt Morgan beating back cancer on his road to QB-1 Jericho High School senior continues to receive chemo treatments as he leads his teammates on the gridiron. Since breast cancer is more commonly found in women ages 40 and older, medical professionals and organizations recommend routine breast cancer screenings for middle-aged and senior women. The glue was slipping quite substantially," she admits. Here's what you need to look out for Yolande Lievens (Ghent University Hospital, Belgium) finds that radiotherapy is underutilised even in Belgium, one of the best-resourced countries in Europe. Nobody tells you how hard the months following cancer treatment are. Patients may also undergo standard of care radiation therapy and receive hormone therapy if appropriate. You have reached the maximum number of saved studies (100). Eric Lim (Royal Brompton and Harefield NHS Trust, London, UK) finds that lung cancer among never-smokers is increasing dramatically. Survival curve estimated using Kaplan-Meier method in the overall analysis population and by pretreatment clinical stage and ER status. Please enter a term before submitting your search. Many online companies offer wigs and caps as well. Get information on latest national and international events & more. I. Amy Lysyczyn: Mines a little bit unique. Patients with prior lobular breast carcinoma in situ (LCIS), atypical hyperplasia, other high risk benign lesions or contralateral DCIS (without evidence of microinvasion) are eligible, Patient must not have stage IV (metastatic) breast cancer, Patient must not be pregnant or breast-feeding due to the potential harm to an unborn fetus and possible risk for adverse events in nursing infants with the treatment regimens being used. To determine the pathologic response to THP neoadjuvant therapy, as assessed by residual cancer burden (RCB). Patients with a history of other non-breast malignancies are eligible if they have been disease-free for at least 5 years, and are deemed by the investigator to be at low risk for recurrence of that malignancy. I ended up in hospital with diviticulitis after the first session. Get the latest health news, diet & fitness information, medical research, health care trends and health issues that affect you and your family on ABCNews.com All treatment-emergent and baseline adverse events and hematological/biochemical toxicities based on laboratory measurements, as well as drug related AEs, will be summarized by NCI CTCAE v5.0 worst grade. November 25 Grey wolves infected with this parasite more likely to become pack leaders PRE-OPERATIVE/NEOADJUVANT THERAPY: Patients receive either paclitaxel or nab-paclitaxel intravenously (IV) on days 1, 8 and 15, or docetaxel IV on day 1 at the discretion of the treating oncologist. After completion of study treatment, patients are followed up every 3 months for 2 years, every 6 months for 2-5 years, then annually for 5-15 years from date of surgery. These skin problems usually develop slowly over days to weeks after your treatment starts. In addition, about 2,400 men are diagnosed with breast cancer each year and some 500 men die from it annually, CDC data shows. These skin problems usually develop slowly over days to weeks after your treatment starts. Here's what you need to look out for WebDon't get scammed this holiday season. Richard Marais (Cancer Research UK Manchester Institute, UK) finds that circulating cell-free DNA is a surrogate marker of tumour burden in patients with metastatic melanoma. The analysis will be descriptive and there will be no statistical test. Study record managers: refer to the Data Element Definitions if submitting registration or results information. 80% of people with cancer also said they are worried about the cost of travel to their hospital appointments with over a third (34%) saying they worry very much. Patients with either hormone receptor -positive or hormone receptor- negative HER2-positive breast cancer are eligible, Patients without nodal involvement (cN0) are eligible if T size > 2.0 cm (T2-3), Patients with nodal involvement (cN1-2) are eligible if T1-3, Patients with clinical T4 or N3 disease are not eligible, Patient must be willing and able (i.e., have no contraindication) to receive standard adjuvant therapy, consisting of HER2-directed therapy, radiation (if indicated) and endocrine therapy (if ER+) if achieving pCR at surgery, Patient with bilateral invasive breast cancers are eligible if both cancers are HER2-positive (as defined in 3.1.3) at least one meets protocol eligibility and neither cancer renders the patient ineligible (i.e. When Anna was diagnosed with breast cancer last year, she expected the worst from her treatment. If you don't remember your password, you can reset it by entering your email address and clicking the Reset Password button. Charlotte Crosby has given fans an update on her mother Letitia's cancer battle, saying her parent is 'doing amazing'. My hair thinned on the first chemo regime, but this last regime of chemo I have kept a full head of hair. I had chemo 20 yrs ago for breast cancer and cant remember it being as bad as Im feeling with this latest chemo for bowel cancer. However, if a patient has a negative axillary physical exam and a baseline MRI without suspicious lymph nodes performed before axillary ultrasound, axillary ultrasound may be omitted. To update your cookie settings, please visit the, Richard Marais (Cancer Research UK Manchester Institute, UK), Eric Lim (Royal Brompton and Harefield NHS Trust, London, UK), Yolande Lievens (Ghent University Hospital, Belgium), Corrigendum to Health-related quality of life in patients with advanced well-differentiated pancreatic and extrapancreatic neuroendocrine tumors treated with surufatinib versus placebo: Results from two randomized, double-blind, phase III trials (SANET-p and SANET-ep) [European Journal of Cancer 169 (2022) 19], Re: Evolution of low HER2 expression between early and advanced-stage breast cancer, Challenges of oncological care in Poland hosting Ukrainian refugees of war, Cancer care for Ukrainian refugees during the first 6 weeks of 2022 Russian invasion An experience of a cancer reference centre in Poland, DeepClassPathway: Molecular pathway aware classification using explainable deep learning, Imaging standardisation in metastatic colorectal cancer: A joint EORTC-ESOI-ESGAR expert consensus recommendation, A randomised phase II trial of a trivalent ganglioside vaccine targeting GM2, GD2and GD3 combined with immunological adjuvant OPT-821 versus OPT-821 alone in metastatic sarcoma patients rendered disease-free by surgery, Persistent immune-related adverse events after cessation of checkpoint inhibitor therapy: Prevalence and impact on patients' health-related quality of life, Adjuvant pembrolizumab versus placebo in resected high-risk stage II melanoma: Health-related quality of life from the randomized phase 3 KEYNOTE-716 study, European Organisation for Research and Treatment of Cancer (EORTC), European Society of Breast Cancer Specialists (EUSOMA), The European cancer burden in 2020: Incidence and mortality estimates for 40 countries and 25 major cancers, The management of desmoid tumours: A joint global consensus-based guideline approach for adult and paediatric patients, European consensus-based interdisciplinary guideline for melanoma. In China the breast cancer rate was one in 100,000 compared to one in ten here. WebSee hot celebrity videos, E! It made me very hypervigilant and ironically, about five months after she died, I found my first mass and lump. Radiotherapy access in Belgium: How far are we from evidence-based utilisation? the patient's mammogram/ breast ultrasound /axillary ultrasound OR their breast MRI). Chemotherapy was effective in shrinking the tumours and, after mastectomy surgery and radiotherapy, followed by a bit more chemo for good measure, Im out the To evaluate the association of detection of CTCs in the blood at baseline, after 3 weeks of THP, after 12 weeks of THP (before surgery), after surgery before any additional therapy, and after completion of HER2-targeted therapy with RFS in patients who achieve pCR or not. ARM A: Patients with pCR after surgery receive trastuzumab and pertuzumab IV on day 1. PRE-OPERATIVE/NEOADJUVANT THERAPY: Patients receive either paclitaxel or nab-paclitaxel IV on days 1, 8 and 15, or docetaxel IV on day 1 at the discretion of the treating oncologist. (Exploratory Clinical Objective) III. WebMSN Health is a leading fitness, wellness, and nutrition resource, with medically reviewed guides, health management tools, and content from respected sources. (If there are more than 1 suspicious axillary nodes, only one clipped node is required). (Exploratory Clinical Objective) IV. Last medically reviewed on June 15, 2021 Cancer / Oncology WebDon't get scammed this holiday season. Chemotherapy was effective in shrinking the tumours and, after mastectomy surgery and radiotherapy, followed by a bit more chemo for good measure, Im out the ARM B: Patients with remaining tumor after surgery receive standard of care trastuzumab emtansine for 14 doses in the absence of disease progression or unacceptable toxicity. POST-OPERATIVE/ADJUVANT THERAPY: Patients with remaining tumor after surgery receive standard of care trastuzumab emtansine for 14 doses in the absence of disease progression or unacceptable toxicity. A man who found the body of his neighbour who had vanished for eight days has described the horror of finding him on top of his house. Check with your cancer center to see what resources are available in your area. "The holding will call into question many other regulations that protect consumers with respect to credit cards, bank accounts, mortgage loans, debt collection, credit reports, and identity theft," tweeted Chris Peterson, a former enforcement attorney at the CFPB who is Oct 14 I ended up in hospital with diviticulitis after the first session. I was high risk. Get the latest health news, diet & fitness information, medical research, health care trends and health issues that affect you and your family on ABCNews.com He tells Helen Saul that a simple blood test could predict overall survival. Following treatment which included a lumpectomy and radiotherapy, all was fine. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load, Patients must not have impaired decision-making capacity, One exception: a patient with a history of T1N0 triple negative breast cancer diagnosed more than 10 years earlier, who remains disease free is eligible, NOTE: Patients currently receiving endocrine therapy for prior contralateral DCIS are eligible, Staging studies (computed tomography [CT] chest/abdomen/pelvis and a bone scan or positron emission tomography [PET]-CT scan) are required for stage III disease or those with abnormal baseline liver function tests (LFTs), symptoms (e.g. WebMSN Health is a leading fitness, wellness, and nutrition resource, with medically reviewed guides, health management tools, and content from respected sources. WebJericho's Brandt Morgan beating back cancer on his road to QB-1 Jericho High School senior continues to receive chemo treatments as he leads his teammates on the gridiron. (Exploratory Correlative Objective) IX. Anatomic Stage IIIA Breast Cancer AJCC v8, Prognostic Stage II Breast Cancer AJCC v8, Prognostic Stage IIA Breast Cancer AJCC v8, Prognostic Stage IIB Breast Cancer AJCC v8, Prognostic Stage IIIA Breast Cancer AJCC v8. Treatment repeats every 21 days for up to 13 cycles in the absence of disease progression or unacceptable toxicity. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Patients also receive trastuzumab IV on day 1 or days 1, 8, and 15, and pertuzumab IV on day 1. Survival curve estimated using Kaplan-Meier method in the overall analysis population and by pretreatment clinical stage and ER status. WebThis trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Masters, Contact: Site Public Contact 302-645-3770, Delaware Clinical and Laboratory Physicians PA, Contact: Site Public Contact 302-623-4450, Medical Oncology Hematology Consultants PA, Christiana Care Health System-Christiana Hospital, Rehoboth Beach, Delaware, United States, 19971, TidalHealth Nanticoke / Allen Cancer Center, Christiana Care Health System-Wilmington Hospital, Wilmington, Delaware, United States, 19801, Kaiser Permanente-Capitol Hill Medical Center, Washington, District of Columbia, United States, 20002, Contact: Site Public Contact 301-548-5743, Washington, District of Columbia, United States, 20016, Contact: Site Public Contact 202-243-2373, Altamonte Springs, Florida, United States, 32701, Contact: Site Public Contact 407-303-2200, Mount Sinai Comprehensive Cancer Center at Aventura, Contact: Site Public Contact 305-674-2625, Principal Investigator: Michael A. Schwartz, UM Sylvester Comprehensive Cancer Center at Aventura, Contact: Site Public Contact 954-461-2180, Celebration, Florida, United States, 34747, Contact: Site Public Contact 407-303-4120, Clearwater, Florida, United States, 33756, Contact: Site Public Contact 855-314-8646, Principal Investigator: Vijaya K. Gadiyaram, UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables, Florida, United States, 33146, Contact: Site Public Contact 305-243-2647, UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach, Florida, United States, 33442, University of Florida Health Science Center - Gainesville, Gainesville, Florida, United States, 32610, Contact: Site Public Contact 352-273-8010, Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Contact: Site Public Contact 954-265-1847, Principal Investigator: Delia C. Guaqueta, Jacksonville, Florida, United States, 32224-9980, Miami Beach, Florida, United States, 33140, University of Miami Miller School of Medicine-Sylvester Cancer Center, UM Sylvester Comprehensive Cancer Center at Kendall, AdventHealth Medical Group Urology at Orlando, Contact: Site Public Contact 407-303-2090, Pembroke Pines, Florida, United States, 33028, Contact: Site Public Contact 954-265-4325, UM Sylvester Comprehensive Cancer Center at Plantation, Plantation, Florida, United States, 33324, Safety Harbor, Florida, United States, 34695, Contact: Site Public Contact 813-870-4760, Winter Haven, Florida, United States, 33881, Contact: Site Public Contact 800-229-2273, Winter Park, Florida, United States, 32792, Contact: Site Public Contact 404-489-9164, Principal Investigator: Kevin M. Kalinsky, Contact: Site Public Contact 888-946-7447, Emory University Hospital/Winship Cancer Institute, Contact: Site Public Contact 404-778-1868, Contact: Site Public Contact 404-851-7115, Contact: Site Public Contact 404-303-3355, Hamilton Medical Center - Peeples Cancer Institute, Contact: Site Public Contact 706-226-8950, Lawrenceville, Georgia, United States, 30046, Lewis Cancer and Research Pavilion at Saint Joseph's/Candler, Contact: Site Public Contact 912-819-5704, Principal Investigator: Alison E. Spellman, Suburban Hematology Oncology Associates - Snellville, Snellville, Georgia, United States, 30078, Thomasville, Georgia, United States, 31792, Contact: Site Public Contact 734-712-3671, Principal Investigator: John M. Schallenkamp, Contact: Site Public Contact 208-381-2774, Saint Alphonsus Cancer Care Center-Caldwell, Coeur d'Alene, Idaho, United States, 83814, Contact: Site Public Contact 406-969-6060, Saint Luke's Cancer Institute - Fruitland, Kootenai Clinic Cancer Services - Post Falls, Saint Luke's Cancer Institute - Twin Falls, Contact: Site Public Contact 618-463-5623, Contact: Site Public Contact 630-978-6212, Principal Investigator: Maria T. Grosse-Perdekamp, Bloomington, Illinois, United States, 61704, Contact: Site Public Contact 309-243-3605, Carbondale, Illinois, United States, 62902, Contact: Site Public Contact 618-457-5200, Carterville, Illinois, United States, 62918, Contact: Site Public Contact 618-985-3333, Centralia, Illinois, United States, 62801, Contact: Site Public Contact 217-876-4762, Contact: Site Public Contact 773-257-5960, Contact: Site Public Contact 312-695-1301, Contact: Site Public Contact 312-942-5498, Principal Investigator: Melody A. Cobleigh, Contact: Site Public Contact 312-355-3046, Principal Investigator: Vijayakrishna K. Gadi, University of Chicago Comprehensive Cancer Center, Contact: Site Public Contact 773-702-8222, Contact: Site Public Contact 800-446-5532, Cancer Care Specialists of Illinois - Decatur, Contact: Site Public Contact 815-285-7800, Effingham, Illinois, United States, 62401, NorthShore University HealthSystem-Evanston Hospital, Contact: Site Public Contact 847-570-2109, Galesburg, Illinois, United States, 61401, Contact: Site Public Contact 309-344-2831, NorthShore University HealthSystem-Glenbrook Hospital, NorthShore University HealthSystem-Highland Park Hospital, Highland Park, Illinois, United States, 60035, Contact: Site Public Contact 815-730-3098, Principal Investigator: Nafisa D. Burhani, Northwestern Medicine Lake Forest Hospital, Lake Forest, Illinois, United States, 60045, Mount Vernon, Illinois, United States, 62864, Contact: Site Public Contact 618-242-4600, UC Comprehensive Cancer Center at Silver Cross, New Lenox, Illinois, United States, 60451, University of Chicago Medicine-Orland Park, Orland Park, Illinois, United States, 60462, Park Ridge, Illinois, United States, 60068, Contact: Site Public Contact 847-384-3621, Contact: Site Public Contact 815-664-4141, Princeton, Illinois, United States, 61356, SwedishAmerican Regional Cancer Center/ACT, Contact: Site Public Contact 779-696-9400, Principal Investigator: Harvey E. Einhorn, Contact: Site Public Contact 563-421-1908, Southern Illinois University School of Medicine, Springfield, Illinois, United States, 62702, Contact: Site Public Contact 217-545-7929, Contact: Site Public Contact 800-444-7541, Springfield, Illinois, United States, 62781, Contact: Site Public Contact 217-528-7541, Washington, Illinois, United States, 61571, Yorkville, Illinois, United States, 60560, Contact: Site Public Contact 317-278-5632, Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, United States, 46202, Indianapolis, Indiana, United States, 46219, Contact: Site Public Contact 317-497-2823, Indianapolis, Indiana, United States, 46227, Indianapolis, Indiana, United States, 46256, Contact: Site Public Contact 765-453-8571, Contact: Site Public Contact 937-528-2900, Contact: Site Public Contact 515-956-4132, Contact: Site Public Contact 515-239-4734, Contact: Site Public Contact 515-689-7658, Contact: Site Public Contact 319-365-4673, Principal Investigator: Deborah W. Wilbur, Oncology Associates at Mercy Medical Center, Contact: Site Public Contact 319-363-2690, Medical Oncology and Hematology Associates-West Des Moines, Contact: Site Public Contact 515-358-6613, Council Bluffs, Iowa, United States, 51503, Contact: Site Public Contact 402-717-1510, Contact: Site Public Contact 515-241-6727, Medical Oncology and Hematology Associates-Des Moines, Contact: Site Public Contact 515-282-2921, Contact: Site Public Contact 515-282-2200, Medical Oncology and Hematology Associates-Laurel, Contact: Site Public Contact 515-241-8704, McFarland Clinic PC-Trinity Cancer Center, Contact: Site Public Contact 515-574-8302, West Des Moines, Iowa, United States, 50266-7700, Contact: Site Public Contact 515-343-1000, West Des Moines, Iowa, United States, 50266, Contact: Site Public Contact 316-268-5374, Garden City, Kansas, United States, 67846, Contact: Site Public Contact 913-948-5588, Independence, Kansas, United States, 67301, Contact: Site Public Contact 316-268-5784, Cancer Center of Kansas-Wichita Medical Arts Tower, Contact: Site Public Contact 800-362-0070, Contact: Site Public Contact 606-327-6499, Bardstown, Kentucky, United States, 40004, Contact: Site Public Contact 859-629-7169, Contact: Site Public Contact 859-523-1934, Lexington, Kentucky, United States, 40503, Contact: Site Public Contact 859-260-6425, Saint Joseph Radiation Oncology Resource Center, Lexington, Kentucky, United States, 40504, Lexington, Kentucky, United States, 40509, University of Kentucky/Markey Cancer Center, Lexington, Kentucky, United States, 40536, Contact: Site Public Contact 859-257-3379, Principal Investigator: Emily F. Marcinkowski, Louisville, Kentucky, United States, 40202, Louisville, Kentucky, United States, 40207, Contact: Site Public Contact 502-897-8592, Louisville, Kentucky, United States, 40215, Louisville, Kentucky, United States, 40245, Baptist Health Madisonville/Merle Mahr Cancer Center, Madisonville, Kentucky, United States, 42431, Contact: Site Public Contact 800-733-2312, Contact: Site Public Contact 270-575-2928, Shepherdsville, Kentucky, United States, 40165, Ochsner Hematology Oncology North Shore - Covington (West Region), Covington, Louisiana, United States, 70433, Contact: Site Public Contact 985-809-5668, Louisiana State University Health Science Center, New Orleans, Louisiana, United States, 70112, Contact: Site Public Contact 504-210-3539, Principal Investigator: Agustin A. Garcia, New Orleans, Louisiana, United States, 70121, Contact: Site Public Contact 504-842-8084, Shreveport, Louisiana, United States, 71103, Contact: Site Public Contact 318-813-1404, Contact: Site Public Contact 207-626-4855, Contact: Site Public Contact 207-338-2500, MaineHealth/SMHC Cancer Care and Blood Disorders-Biddeford, Contact: Site Public Contact 800-987-3005, Principal Investigator: Sarah J. Sinclair, Maine Center for Cancer Medicine-Kennebunk, Contact: Site Public Contact 207-396-8670, MaineHealth/SMHC Cancer Care and Blood Disorders-Sanford, Maine Center for Cancer Medicine-Scarborough, Contact: Site Public Contact 207-396-8090, South Portland, Maine, United States, 04106, Annapolis, Maryland, United States, 21401, Contact: Site Public Contact 443-481-1320, Baltimore, Maryland, United States, 21215, Contact: Site Public Contact 410-601-6120, Kaiser Permanente-Woodlawn Medical Center, Baltimore, Maryland, United States, 21244, Contact: Site Public Contact 301-816-7218, Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland, United States, 21287, Contact: Site Public Contact 410-955-8804, Kaiser Permanente-Gaithersburg Medical Center, Gaithersburg, Maryland, United States, 20879, Kaiser Permanente - Kensington Medical Center, Kensington, Maryland, United States, 20895, Contact: Site Public Contact 301-816-7446, Randallstown, Maryland, United States, 21133, William E Kahlert Regional Cancer Center/Sinai Hospital, Westminster, Maryland, United States, 21157, Beverly, Massachusetts, United States, 01915, Contact: Site Public Contact 978-922-3000 ext 2405, Principal Investigator: Corrine L. Zarwan, Boston, Massachusetts, United States, 02111, Contact: Site Public Contact 617-636-5000, Principal Investigator: Rachel J. Buchsbaum, Boston, Massachusetts, United States, 02118, Contact: Site Public Contact 617-638-8265, Boston, Massachusetts, United States, 02215, Contact: Site Public Contact 617-667-9925, Contact: Site Public Contact 877-442-3324, Burlington, Massachusetts, United States, 01805, Contact: Site Public Contact 781-744-3421, Gloucester, Massachusetts, United States, 01930, Contact: Site Public Contact 978-283-4000 ext 559, Lowell, Massachusetts, United States, 01854, Contact: Site Public Contact 978-788-7084, Dana-Farber/Brigham and Women's Cancer Center at Milford Regional, Milford, Massachusetts, United States, 01757, Contact: Site Public Contact 877-332-4294, Peabody, Massachusetts, United States, 01960, Dana-Farber/Brigham and Women's Cancer Center at South Shore, South Weymouth, Massachusetts, United States, 02190, Contact: Site Public Contact 781-624-5000, Springfield, Massachusetts, United States, 01199, Contact: Site Public Contact 413-794-3565, Principal Investigator: Grace Makari-Judson, Winchester, Massachusetts, United States, 01890, Contact: Site Public Contact 888-823-5923, UMass Memorial Medical Center - University Campus, Worcester, Massachusetts, United States, 01655, Contact: Site Public Contact 508-856-3216, Principal Investigator: Kathryn L. Edmiston, University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States, 48109, Contact: Site Public Contact 800-865-1125, Principal Investigator: Kathleen A. Kemmer, Battle Creek, Michigan, United States, 49017, Contact: Site Public Contact 616-391-1230, University of Michigan - Brighton Center for Specialty Care, Wayne State University/Karmanos Cancer Institute, Contact: Site Public Contact 313-576-9790, Farmington Hills, Michigan, United States, 48334, Helen DeVos Children's Hospital at Spectrum Health, Grand Rapids, Michigan, United States, 49503, Kalamazoo, Michigan, United States, 49007, Kalamazoo, Michigan, United States, 49009, Kalamazoo, Michigan, United States, 49048, Cancer and Hematology Centers of Western Michigan - Norton Shores, Norton Shores, Michigan, United States, 49444, Contact: Site Public Contact 248-849-5332, Principal Investigator: Cynthia M. Vakhariya, Reed City, Michigan, United States, 49677, Saint Joseph, Michigan, United States, 49085, Ascension Providence Hospitals - Southfield, Southfield, Michigan, United States, 48075, Traverse City, Michigan, United States, 49684, Contact: Site Public Contact 218-786-3308, Contact: Site Public Contact 218-828-2880, Contact: Site Public Contact 218-333-5000, Essentia Health Saint Joseph's Medical Center, Brainerd, Minnesota, United States, 56401, Burnsville, Minnesota, United States, 55337, Contact: Site Public Contact 952-993-1517, Cambridge, Minnesota, United States, 55008, Coon Rapids, Minnesota, United States, 55433, Deer River, Minnesota, United States, 56636, Essentia Health Saint Mary's - Detroit Lakes Clinic, Detroit Lakes, Minnesota, United States, 56501, Essentia Health Saint Mary's Medical Center, Contact: Site Public Contact 218-365-7900, Lake Region Healthcare Corporation-Cancer Care, Fergus Falls, Minnesota, United States, 56537, Essentia Health - International Falls Clinic, International Falls, Minnesota, United States, 56649, Contact: Site Public Contact 218-283-9431, Fairview Clinics and Surgery Center Maple Grove, Maple Grove, Minnesota, United States, 55369, Minnesota Oncology Hematology PA-Maplewood, Maplewood, Minnesota, United States, 55109, Minneapolis, Minnesota, United States, 55407, Minneapolis, Minnesota, United States, 55415, Minneapolis, Minnesota, United States, 55454, Monticello, Minnesota, United States, 55362, Moose Lake, Minnesota, United States, 55767, Contact: Site Public Contact 218-485-4481, Park Rapids, Minnesota, United States, 56470, Princeton, Minnesota, United States, 55371, Robbinsdale, Minnesota, United States, 55422, Rochester, Minnesota, United States, 55905, Contact: Site Public Contact 855-776-0015, Principal Investigator: Ciara C. O'Sullivan, Coborn Cancer Center at Saint Cloud Hospital, Saint Cloud, Minnesota, United States, 56303, Contact: Site Public Contact 877-229-4907, Principal Investigator: Donald J. Jurgens, Saint Louis Park, Minnesota, United States, 55416, Saint Paul, Minnesota, United States, 55101, Saint Paul, Minnesota, United States, 55102, Sandstone, Minnesota, United States, 55072, Shakopee, Minnesota, United States, 55379, Stillwater, Minnesota, United States, 55082, Thief River Falls, Minnesota, United States, 56701, Contact: Site Public Contact 605-312-3320, Virginia, Minnesota, United States, 55792, Minnesota Oncology Hematology PA-Woodbury, Woodbury, Minnesota, United States, 55125, Baptist Memorial Hospital and Cancer Center-Golden Triangle, Columbus, Mississippi, United States, 39705, Contact: Site Public Contact 901-226-1366, Grenada, Mississippi, United States, 38901, Jackson, Mississippi, United States, 39216, Contact: Site Public Contact 601-815-6700, Baptist Memorial Hospital and Cancer Center-Union County, New Albany, Mississippi, United States, 38652, Baptist Memorial Hospital and Cancer Center-Oxford, Oxford, Mississippi, United States, 38655, Pascagoula, Mississippi, United States, 39581, Baptist Memorial Hospital and Cancer Center-Desoto, Southhaven, Mississippi, United States, 38671, Saint Louis Cancer and Breast Institute-Ballwin, Contact: Site Public Contact 314-251-7058, Contact: Site Public Contact 417-269-4520, Cape Girardeau, Missouri, United States, 63703, Contact: Site Public Contact 573-334-2230, Contact: Site Public Contact 573-651-5550, Chesterfield, Missouri, United States, 63017, Contact: Site Public Contact 314-205-6936, Contact: Site Public Contact 573-882-7440, Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri, United States, 63141, Contact: Site Public Contact 800-600-3606, Farmington, Missouri, United States, 63640, Contact: Site Public Contact 314-996-5569, Jefferson City, Missouri, United States, 65109, Contact: Site Public Contact 573-632-4814, Contact: Site Public Contact 417-347-4030, Contact: Site Public Contact 417-556-3074, Contact: Site Public Contact 573-458-7504, Contact: Site Public Contact 573-458-6379, Saint Joseph, Missouri, United States, 64506, Contact: Site Public Contact 816-271-7937, Saint Louis Cancer and Breast Institute-South City, Saint Louis, Missouri, United States, 63109, Contact: Site Public Contact 314-353-1870, Saint Louis, Missouri, United States, 63110, Saint Louis, Missouri, United States, 63128, Saint Louis, Missouri, United States, 63129, Saint Louis, Missouri, United States, 63131, Siteman Cancer Center at Christian Hospital, Saint Louis, Missouri, United States, 63136, Saint Louis, Missouri, United States, 63141, Contact: Site Public Contact 314-251-7066, Siteman Cancer Center at Saint Peters Hospital, Saint Peters, Missouri, United States, 63376, Sainte Genevieve County Memorial Hospital, Sainte Genevieve, Missouri, United States, 63670, Springfield, Missouri, United States, 65804, Springfield, Missouri, United States, 65807, Missouri Baptist Outpatient Center-Sunset Hills, Sunset Hills, Missouri, United States, 63127, Washington, Missouri, United States, 63090, Contact: Site Public Contact 636-390-1600, Contact: Site Public Contact 800-996-2663, Benefis Healthcare- Sletten Cancer Institute, Great Falls, Montana, United States, 59405, Saint Patrick Hospital - Community Hospital, Contact: Site Public Contact 406-327-3118, Contact: Site Public Contact 402-559-6941, Principal Investigator: Jairam Krishnamurthy, Grand Island, Nebraska, United States, 68803, Contact: Site Public Contact 402-334-4773, Contact: Site Public Contact 308-865-7963, Contact: Site Public Contact 855-313-2409, Contact: Site Public Contact 402-327-7363, Southeast Nebraska Cancer Center - 68th Street Place, Contact: Site Public Contact 402-559-5600, Alegent Health Bergan Mercy Medical Center, Papillion, Nebraska, United States, 68046, Carson City, Nevada, United States, 89703, Comprehensive Cancer Centers of Nevada - Henderson, Comprehensive Cancer Centers of Nevada-Horizon Ridge, Comprehensive Cancer Centers of Nevada-Southeast Henderson, Urology Specialists of Nevada - Green Valley, University Medical Center of Southern Nevada, Radiation Oncology Centers of Nevada Central, HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway, HealthCare Partners Medical Group Oncology/Hematology-San Martin, Urology Specialists of Nevada - Southwest, Radiation Oncology Centers of Nevada Southeast, Comprehensive Cancer Centers of Nevada - Northwest, HealthCare Partners Medical Group Oncology/Hematology-Tenaya, Urology Specialists of Nevada - Northwest, Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Comprehensive Cancer Centers of Nevada - Town Center, Comprehensive Cancer Centers of Nevada-Summerlin, Las Vegas, Nevada, United States, 89148-2405, HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills, Comprehensive Cancer Centers of Nevada - Central Valley, New Hampshire Oncology Hematology PA-Concord, Concord, New Hampshire, United States, 03301, Contact: Site Public Contact 603-224-2556, Principal Investigator: Douglas J. Weckstein, Manchester, New Hampshire, United States, 03103, Contact: Site Public Contact 800-339-6484, Basking Ridge, New Jersey, United States, 07920, Contact: Site Public Contact 212-639-7592, Trinitas Hospital and Comprehensive Cancer Center - Williamson Street Campus, Elizabeth, New Jersey, United States, 07207, Contact: Site Public Contact 908-994-8000, Hackensack, New Jersey, United States, 07601, Contact: Site Public Contact 201-996-2879, The Cancer Institute of New Jersey Hamilton, Hamilton, New Jersey, United States, 08690, Contact: Site Public Contact 609-631-6946, Jersey City, New Jersey, United States, 07302, Lakewood, New Jersey, United States, 08701, Contact: Site Public Contact 732-923-6564, Livingston, New Jersey, United States, 07039, Contact: Site Public Contact 973-322-2934, Long Branch, New Jersey, United States, 07740, Middletown, New Jersey, United States, 07748, Montvale, New Jersey, United States, 07645, Morristown, New Jersey, United States, 07960, Contact: Site Public Contact 973-971-5900, Mullica Hill, New Jersey, United States, 08062, Contact: Site Public Contact 856-508-3500, New Brunswick, New Jersey, United States, 08903, Contact: Site Public Contact 732-235-7356, Contact: Site Public Contact 973-926-7230, Sidney Kimmel Cancer Center Washington Township, Contact: Site Public Contact 215-600-9151, Principal Investigator: Allison M. Zibelli, Robert Wood Johnson University Hospital Somerset, Somerville, New Jersey, United States, 08876, Contact: Site Public Contact 908-685-2481, Contact: Site Public Contact 908-522-2043, Teaneck, New Jersey, United States, 07666, Toms River, New Jersey, United States, 08755, Contact: Site Public Contact 732-557-8294, Vineland, New Jersey, United States, 08360, Contact: Site Public Contact 856-641-7933, Lovelace Medical Center-Saint Joseph Square, Albuquerque, New Mexico, United States, 87102, Contact: Site Public Contact 505-272-0530, Principal Investigator: Jacklyn M. Nemunaitis, Contact: Site Public Contact 505-925-0366, Albuquerque, New Mexico, United States, 87109, Albuquerque, New Mexico, United States, 87110, Las Cruces, New Mexico, United States, 88011, Contact: Site Public Contact 575-556-6545, Presbyterian Rust Medical Center/Jorgensen Cancer Center, Rio Rancho, New Mexico, United States, 87124, Hematology Oncology Associates of Central New York-Auburn, Contact: Site Public Contact 315-472-7504, Principal Investigator: Jeffrey J. Kirshner, Montefiore Medical Center-Einstein Campus, Contact: Site Public Contact 718-379-6866, Montefiore Medical Center-Weiler Hospital, New York-Presbyterian/Brooklyn Methodist Hospital, Contact: Site Public Contact 718-780-3677, Contact: Site Public Contact 718-765-2500, Contact: Site Public Contact 800-767-9355, Cancer Institute at Saint Francis Hospital, East Hills, New York, United States, 11548, Hematology Oncology Associates of Central New York-East Syracuse, East Syracuse, New York, United States, 13057, The New York Hospital Medical Center of Queens, Glens Falls, New York, United States, 12801, Contact: Site Public Contact 518-926-6700, Principal Investigator: Darci A. Gaiotti-Grubbs, Contact: Site Public Contact 212-263-4432, Contact: Site Public Contact 212-824-7309, Laura and Isaac Perlmutter Cancer Center at NYU Langone, NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, Contact: Site Public Contact 212-305-6361, Contact: Site Public Contact 212-746-1848, Principal Investigator: Eleni Andreopoulou, Contact: Site Public Contact 315-464-8230, Principal Investigator: Abirami Sivapiragasam, Rochester, New York, United States, 14642, Contact: Site Public Contact 585-275-5830, Stony Brook, New York, United States, 11794, Contact: Site Public Contact 800-862-2215, State University of New York Upstate Medical University, Contact: Site Public Contact 315-464-5476, Hematology Oncology Associates of Central New York-Onondaga Hill, Uniondale, New York, United States, 11553, Valley Stream, New York, United States, 11580, White Plains, New York, United States, 10601, Contact: Site Public Contact 914-849-7582, Albemarle, North Carolina, United States, 28002, Contact: Site Public Contact 800-804-9376, Cary, North Carolina, United States, 27518, Contact: Site Public Contact 919-784-2500, UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, United States, 27599, Contact: Site Public Contact 877-668-0683, Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina, United States, 28203, Novant Health Presbyterian Medical Center, Charlotte, North Carolina, United States, 28204, Contact: Site Public Contact 980-201-6360, Principal Investigator: Kimberly S. Strickland, Novant Health Carolina Surgical - Randolph, Charlotte, North Carolina, United States, 28207, Charlotte, North Carolina, United States, 28210, Contact: Site Public Contact 980-442-2000, Atrium Health University City/LCI-University, Charlotte, North Carolina, United States, 28262, Southeastern Medical Oncology Center-Clinton, Clinton, North Carolina, United States, 28328, Contact: Site Public Contact 919-587-9084, Concord, North Carolina, United States, 28025, Forest City, North Carolina, United States, 28043, Rex Hematology Oncology Associates-Garner, Garner, North Carolina, United States, 27529, Southeastern Medical Oncology Center-Goldsboro, Goldsboro, North Carolina, United States, 27534, Novant Health Breast Surgery - Greensboro, Greensboro, North Carolina, United States, 27403, Contact: Site Public Contact 336-660-5540, Principal Investigator: Judith O. Hopkins, Hendersonville, North Carolina, United States, 28791, Contact: Site Public Contact 828-696-4716, University of North Carolina-Hillsborough Campus, Hillsborough, North Carolina, United States, 27278, Novant Health Cancer Institute - Huntersville, Huntersville, North Carolina, United States, 28078, Novant Health Presbyterian Medical Center Huntersville, Southeastern Medical Oncology Center-Jacksonville, Jacksonville, North Carolina, United States, 28546, Contact: Site Public Contact 910-587-9084, Novant Health Cancer Institute - Kernersville, Kernersville, North Carolina, United States, 27284, Contact: Site Public Contact 336-718-8335, Lincolnton, North Carolina, United States, 28092, Matthews, North Carolina, United States, 28104, Contact: Site Public Contact 980-442-0600, Matthews, North Carolina, United States, 28105, Novant Health Cancer Institute - Matthews, Monroe, North Carolina, United States, 28112, Novant Health Cancer Institute - Mooresville, Mooresville, North Carolina, United States, 28117, Novant Health Cancer Institute - Mount Airy, Mount Airy, North Carolina, United States, 27030, FirstHealth of the Carolinas-Moore Regional Hospital, Pinehurst, North Carolina, United States, 28374, Rex Hematology Oncology Associates-Blue Ridge, Raleigh, North Carolina, United States, 27607, Contact: Site Public Contact 919-784-7209, Raleigh, North Carolina, United States, 27614, Salisbury, North Carolina, United States, 28144, Contact: Site Public Contact 704-210-5000, Shelby, North Carolina, United States, 28150, Novant Health Cancer Institute - Statesville, Statesville, North Carolina, United States, 28625, Novant Health Cancer Institute - Thomasville, Thomasville, North Carolina, United States, 27360, Novant Health Cancer Institute - Wilkesboro, Wilkesboro, North Carolina, United States, 28659, Winston-Salem, North Carolina, United States, 27103, Bismarck, North Dakota, United States, 58501, Contact: Site Public Contact 701-323-5760, Essentia Health Cancer Center-South University Clinic, Fargo, North Dakota, United States, 58103, Contact: Site Public Contact 701-234-6161, Fargo, North Dakota, United States, 58104, Contact: Site Public Contact 800-437-4010, Fargo, North Dakota, United States, 58122, Jamestown, North Dakota, United States, 58401, Contact: Site Public Contact 330-363-1250, Principal Investigator: Sunitha Vemulapalli, Contact: Site Public Contact 330-363-7274, Contact: Site Public Contact 513-585-0844, Principal Investigator: Alexander N. Starodub, Contact: Site Public Contact 513-853-1300, Contact: Site Public Contact 216-778-8526, Ohio State University Comprehensive Cancer Center, Contact: Site Public Contact 800-293-5066, Principal Investigator: Sagar D. Sardesai, Dayton Physician LLC-Miami Valley Hospital North, Atrium Medical Center-Middletown Regional Hospital, Franklin, Ohio, United States, 45005-1066, Contact: Site Public Contact 888-874-7000, Wright-Patterson Air Force Base, Ohio, United States, 45433, Cancer Centers of Southwest Oklahoma Research, Contact: Site Public Contact 877-231-4440, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States, 73104, Contact: Site Public Contact 405-271-8777, Oklahoma City, Oklahoma, United States, 73120, Contact: Site Public Contact 405-752-3402, Saint Alphonsus Medical Center-Baker City, Contact: Site Public Contact 541-706-2909, Contact: Site Public Contact 503-215-2614, Providence Cancer Institute Clackamas Clinic, Contact: Site Public Contact 541-269-8392, Contact: Site Public Contact 503-413-2150, Principal Investigator: Onyekachi H. Ogbonna, Legacy Good Samaritan Hospital and Medical Center, Contact: Site Public Contact 800-220-4937, Contact: Site Public Contact 503-413-1742, Altoona, Pennsylvania, United States, 16601, UPMC-Heritage Valley Health System Beaver, Beaver, Pennsylvania, United States, 15009, Contact: Site Public Contact 412-389-5208, Bryn Mawr, Pennsylvania, United States, 19010, Contact: Site Public Contact 484-476-2649, Principal Investigator: Albert S. DeNittis, UPMC Hillman Cancer Center at Butler Health System, Butler, Pennsylvania, United States, 16001, Camp Hill, Pennsylvania, United States, 17011, Contact: Site Public Contact 717-975-8900, Carlisle, Pennsylvania, United States, 17015, Christiana Care Health System-Concord Health Center, Chadds Ford, Pennsylvania, United States, 19317, Chambersburg, Pennsylvania, United States, 17201, Principal Investigator: Joseph Kannarkatt, Contact: Site Public Contact 717-217-6020, Collegeville, Pennsylvania, United States, 19426, UPMC Hillman Cancer Center - Passavant - Cranberry, Cranberry Township, Pennsylvania, United States, 16066, Danville, Pennsylvania, United States, 17822, Contact: Site Public Contact 570-271-5251, Fox Chase Cancer Center - East Norriton Hospital Outpatient Center, East Norriton, Pennsylvania, United States, 19401, Ephrata, Pennsylvania, United States, 17522, Contact: Site Public Contact 717-721-4840, Contact: Site Public Contact 814-452-5000, Principal Investigator: Christie J. Hilton, Exton, Pennsylvania, United States, 19341, Farrell, Pennsylvania, United States, 16121, Gettysburg, Pennsylvania, United States, 17325, Contact: Site Public Contact 877-441-7957, UPMC Cancer Centers - Arnold Palmer Pavilion, Greensburg, Pennsylvania, United States, 15601, Contact: Site Public Contact 724-838-1900, Greenville, Pennsylvania, United States, 16125, Hanover, Pennsylvania, United States, 17331, Contact: Site Public Contact 717-632-1559, Harrisburg, Pennsylvania, United States, 17101, UPMC Pinnacle Cancer Center/Community Osteopathic Campus, Harrisburg, Pennsylvania, United States, 17109, Contact: Site Public Contact 717-724-6765, Geisinger Medical Center-Cancer Center Hazleton, Hazleton, Pennsylvania, United States, 18201, Contact: Site Public Contact 570-459-2901, Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania, United States, 17033-0850, Contact: Site Public Contact 717-531-3779, Principal Investigator: Cristina I. Truica, Indiana, Pennsylvania, United States, 15701, Jefferson Hills, Pennsylvania, United States, 15025, Contact: Site Public Contact 412-359-3043, UPMC-Johnstown/John P. Murtha Regional Cancer Center, Johnstown, Pennsylvania, United States, 15901, Contact: Site Public Contact 814-534-4724, Lebanon, Pennsylvania, United States, 17042, Contact: Site Public Contact 717-741-8303, Lewisburg, Pennsylvania, United States, 17837, Contact: Site Public Contact 570-374-8555, Lewistown, Pennsylvania, United States, 17044, Contact: Site Public Contact 717-242-7703, McKeesport, Pennsylvania, United States, 15132, Contact: Site Public Contact 412-647-8073, UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion, Mechanicsburg, Pennsylvania, United States, 17050, Media, Pennsylvania, United States, 19063, Monroeville, Pennsylvania, United States, 15146, Contact: Site Public Contact 412-858-7746, UPMC-Coraopolis/Heritage Valley Radiation Oncology, Contact: Site Public Contact 412-604-2020, UPMC Hillman Cancer Center - Part of Frick Hospital, Mount Pleasant, Pennsylvania, United States, 15666, Arnold Palmer Cancer Center Medical Oncology Norwin, N. Huntingdon, Pennsylvania, United States, 15642, Natrona Heights, Pennsylvania, United States, 15065, Contact: Site Public Contact 724-230-3030, New Castle, Pennsylvania, United States, 16105, Newtown Square, Pennsylvania, United States, 19073, Paoli, Pennsylvania, United States, 19301, University of Pennsylvania/Abramson Cancer Center, Philadelphia, Pennsylvania, United States, 19104, Contact: Site Public Contact 800-474-9892, Principal Investigator: Angela M. DeMichele, Philadelphia, Pennsylvania, United States, 19107, Philadelphia, Pennsylvania, United States, 19111, Contact: Site Public Contact 215-728-4790, Philadelphia, Pennsylvania, United States, 19114, Philadelphia, Pennsylvania, United States, 19140, Contact: Site Public Contact 215-728-2983, Philadelphia, Pennsylvania, United States, 19148, Pittsburgh, Pennsylvania, United States, 15212, Contact: Site Public Contact 877-284-2000, Pittsburgh, Pennsylvania, United States, 15213, Contact: Site Public Contact 412-647-2811, Pittsburgh, Pennsylvania, United States, 15215, Contact: Site Public Contact 412-784-4900, Pittsburgh, Pennsylvania, United States, 15219, Contact: Site Public Contact 800-533-8762, Pittsburgh, Pennsylvania, United States, 15224, Contact: Site Public Contact 412-578-5000, University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania, United States, 15232, Pittsburgh, Pennsylvania, United States, 15237, Contact: Site Public Contact 412-367-6454, Pittsburgh, Pennsylvania, United States, 15243, Contact: Site Public Contact 412-502-3920, Pottsville, Pennsylvania, United States, 17901, Contact: Site Public Contact 800-275-6401, Penn State Health Saint Joseph Medical Center, Reading, Pennsylvania, United States, 19605, Contact: Site Public Contact 610-378-2336, Scranton, Pennsylvania, United States, 18510, Contact: Site Public Contact 570-703-4768, Selinsgrove, Pennsylvania, United States, 17870, Seneca, Pennsylvania, United States, 16346, Contact: Site Public Contact 814-676-7900, State College, Pennsylvania, United States, 16801, Uniontown, Pennsylvania, United States, 15401, UPMC Uniontown Hospital Radiation Oncology, Contact: Site Public Contact 724-437-2503, Washington, Pennsylvania, United States, 15301, UPMC Washington Hospital Radiation Oncology, Contact: Site Public Contact 724-223-3788, West Chester, Pennsylvania, United States, 19380, Contact: Site Public Contact 610-431-5297, Principal Investigator: Maureen R. Hewitt, UPMC West Mifflin-Cancer Center Jefferson, West Mifflin, Pennsylvania, United States, 15122, Contact: Site Public Contact 412-653-8100, West Reading, Pennsylvania, United States, 19611, Contact: Site Public Contact 610-988-9323, Principal Investigator: Terrence P. Cescon, Wexford, Pennsylvania, United States, 15090, Geisinger Wyoming Valley/Henry Cancer Center, Wilkes-Barre, Pennsylvania, United States, 18711, Williamsport, Pennsylvania, United States, 17754, Willow Grove, Pennsylvania, United States, 19090, Wynnewood, Pennsylvania, United States, 19096, Contact: Site Public Contact 717-741-9229, Contact: Site Public Contact 717-724-6760, Providence, Rhode Island, United States, 02905, Contact: Site Public Contact 401-274-1122, Warwick, Rhode Island, United States, 02886, Contact: Site Public Contact 401-737-7010, Smilow Cancer Hospital Care Center - Westerly, Westerly, Rhode Island, United States, 02891, Bluffton, South Carolina, United States, 29910, Greenville, South Carolina, United States, 29601, Contact: Site Public Contact 864-603-6213, Greenville, South Carolina, United States, 29607, Hilton Head Island, South Carolina, United States, 29926-3827, Rock Hill, South Carolina, United States, 29732, Aberdeen, South Dakota, United States, 57401, Contact: Site Public Contact 605-622-8700, Sioux Falls, South Dakota, United States, 57105, Contact: Site Public Contact 605-322-3095, Contact: Site Public Contact 423-578-8538, Principal Investigator: Asheesh Shipstone, Baptist Memorial Hospital and Cancer Center-Collierville, Collierville, Tennessee, United States, 38017, Vanderbilt-Ingram Cancer Center Cool Springs, Franklin, Tennessee, United States, 37067, Contact: Site Public Contact 800-811-8480, Principal Investigator: Vandana G. Abramson, Kingsport, Tennessee, United States, 37660, Wellmont Holston Valley Hospital and Medical Center, Baptist Memorial Hospital and Cancer Center-Memphis, Vanderbilt Breast Center at One Hundred Oaks, Nashville, Tennessee, United States, 37204, Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee, United States, 37232, Contact: Site Public Contact 214-590-5582, UT Southwestern/Simmons Cancer Center-Dallas, Contact: Site Public Contact 214-648-7097, Tarrant County Hospital District/JPS Health Network, Contact: Site Public Contact 817-702-5913, Principal Investigator: Bassam S. Ghabach, UT Southwestern/Simmons Cancer Center-Fort Worth, Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Contact: Site Public Contact 713-798-1354, Principal Investigator: Mothaffar F. Rimawi, Contact: Site Public Contact 713-873-2000, UT Southwestern Clinical Center at Richardson/Plano, Contact: Site Public Contact 972-669-7044, Contact: Site Public Contact 888-424-2100, University of Utah Sugarhouse Health Center, Salt Lake City, Utah, United States, 84106, Huntsman Cancer Institute/University of Utah, Salt Lake City, Utah, United States, 84112, Chesapeake, Virginia, United States, 23320, Gloucester, Virginia, United States, 23061, Kaiser Permanente Tysons Corner Medical Center, Contact: Site Public Contact 240-632-4284, Bon Secours Memorial Regional Medical Center, Mechanicsville, Virginia, United States, 23116, Contact: Site Public Contact 804-893-8663, Midlothian, Virginia, United States, 23113, Midlothian, Virginia, United States, 23114, Newport News, Virginia, United States, 23601, Portsmouth, Virginia, United States, 23707, Bon Secours Cancer Institute at Reynolds Crossing, Principal Investigator: Hetal R. Vachhani, Virginia Commonwealth University/Massey Cancer Center, South Hill, Virginia, United States, 23970, Contact: Site Public Contact 434-774-2442, Bon Secours Health Center at Harbour View, Peninsula Cancer Institute-Cancer Specialists of Tidewater, Virginia Beach, Virginia, United States, 23454, Williamsburg, Virginia, United States, 23185, Providence Regional Cancer System-Aberdeen, Aberdeen, Washington, United States, 98520, Contact: Site Public Contact 360-412-8958, Bellevue, Washington, United States, 98004, Contact: Site Public Contact 425-688-5407, Bellingham, Washington, United States, 98225, Contact: Site Public Contact 360-788-8238, Harrison HealthPartners Hematology and Oncology-Bremerton, Bremerton, Washington, United States, 98310, Contact: Site Public Contact 308-398-6518, Contact: Site Public Contact 253-426-6882, Providence Regional Cancer System-Centralia, Centralia, Washington, United States, 98531, Edmonds, Washington, United States, 98026, Contact: Site Public Contact 206-215-3086, Enumclaw, Washington, United States, 98022, Everett, Washington, United States, 98201, Contact: Site Public Contact 425-261-3529, Federal Way, Washington, United States, 98003, Issaquah, Washington, United States, 98029, Kennewick, Washington, United States, 99336, Contact: Site Public Contact 509-783-4637, Lakewood, Washington, United States, 98499, Longview, Washington, United States, 98632, Contact: Site Public Contact 360-514-2016, Port Townsend, Washington, United States, 98368, Contact: Site Public Contact 360-344-3091, Harrison HealthPartners Hematology and Oncology-Poulsbo, Poulsbo, Washington, United States, 98370, Contact: Site Public Contact 425-228-3440, Seattle, Washington, United States, 98104, Seattle, Washington, United States, 98107, Seattle, Washington, United States, 98122-5711, Seattle, Washington, United States, 98122, PeaceHealth United General Medical Center, Sedro-Woolley, Washington, United States, 98284, Providence Regional Cancer System-Shelton, Shelton, Washington, United States, 98584, Franciscan Research Center-Northwest Medical Plaza, Vancouver, Washington, United States, 98664, Contact: Site Public Contact 360-514-3940, Legacy Cancer Institute Medical Oncology and Day Treatment, Vancouver, Washington, United States, 98684, Vancouver, Washington, United States, 98686, Providence Saint Mary Regional Cancer Center, Walla Walla, Washington, United States, 99362, Contact: Site Public Contact 509-897-5993, North Star Lodge Cancer Center at Yakima Valley Memorial Hospital, Contact: Site Public Contact 509-574-3535, West Virginia University Charleston Division, Charleston, West Virginia, United States, 25304, Contact: Site Public Contact 304-388-9944, Principal Investigator: Steven J. Jubelirer, Contact: Site Public Contact 715-623-9869, Appleton, Wisconsin, United States, 54911, Contact: Site Public Contact 920-364-3605, Appleton, Wisconsin, United States, 54915, Contact: Site Public Contact 414-635-6420, Principal Investigator: Jonathan S. Treisman, Ascension Southeast Wisconsin Hospital - Elmbrook Campus, Brookfield, Wisconsin, United States, 53045, Burlington, Wisconsin, United States, 53105, Contact: Site Public Contact 414-302-2304, Chippewa Falls, Wisconsin, United States, 54729, Contact: Site Public Contact 800-782-8581, Eau Claire, Wisconsin, United States, 54701, Contact: Site Public Contact 920-433-8889, Principal Investigator: Brian L. Burnette, Marshfield Medical Center-EC Cancer Center, Mayo Clinic Health System-Eau Claire Clinic, Mayo Clinic Health System Eau Claire Hospital-Luther Campus, Eau Claire, Wisconsin, United States, 54703, Ascension Saint Francis - Reiman Cancer Center, Franklin, Wisconsin, United States, 53132, Ascension Southeast Wisconsin Hospital - Franklin, Aurora Health Care Germantown Health Center, Germantown, Wisconsin, United States, 53022, Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin, United States, 54301, Saint Vincent Hospital Cancer Center at Saint Mary's, Green Bay, Wisconsin, United States, 54303, Green Bay, Wisconsin, United States, 54311, Johnson Creek, Wisconsin, United States, 53038, Contact: Site Public Contact 920-699-3500, La Crosse, Wisconsin, United States, 54601, Contact: Site Public Contact 608-775-2385, Mayo Clinic Health System-Franciscan Healthcare, Ladysmith, Wisconsin, United States, 54848, University of Wisconsin Carbone Cancer Center, Contact: Site Public Contact 800-622-8922, Marinette, Wisconsin, United States, 54143, Marshfield, Wisconsin, United States, 54449, Contact: Site Public Contact 715-847-2353, Ascension Columbia Saint Mary's Hospital Ozaukee, Milwaukee, Wisconsin, United States, 53209, Ascension Southeast Wisconsin Hospital - Saint Joseph Campus, Milwaukee, Wisconsin, United States, 53210, Ascension Columbia Saint Mary's Hospital - Milwaukee, Milwaukee, Wisconsin, United States, 53211, Milwaukee, Wisconsin, United States, 53215, Milwaukee, Wisconsin, United States, 53233, Minocqua, Wisconsin, United States, 54548, ThedaCare Regional Medical Center - Neenah, New Richmond, Wisconsin, United States, 54017, Saint Vincent Hospital Cancer Center at Oconto Falls, Oconto Falls, Wisconsin, United States, 54154, Contact: Site Public Contact 920-831-8900, Rhinelander, Wisconsin, United States, 54501, Rice Lake, Wisconsin, United States, 54868, Sheboygan, Wisconsin, United States, 53081, Stevens Point, Wisconsin, United States, 54481, Marshfield Medical Center-River Region at Stevens Point, Stevens Point, Wisconsin, United States, 54482, Saint Vincent Hospital Cancer Center at Sturgeon Bay, Sturgeon Bay, Wisconsin, United States, 54235-1495, Essentia Health Saint Mary's Hospital - Superior, Superior, Wisconsin, United States, 54880, Contact: Site Public Contact 701-364-6272, Two Rivers, Wisconsin, United States, 54241, Contact: Site Public Contact 877-405-6866, Ascension Medical Group Southeast Wisconsin - Mayfair Road, Wauwatosa, Wisconsin, United States, 53226, West Allis, Wisconsin, United States, 53227, Wisconsin Rapids, Wisconsin, United States, 54494, Contact: Site Public Contact 715-422-7718, Marshfield Clinic - Wisconsin Rapids Center, Cancer Center-Metro Medical Center Bayamon, Contact: Site Public Contact 787-395-7085, Contact: Site Public Contact 787-653-3434, Contact: Site Public Contact 787-848-0606, Contact: Site Public Contact 787-274-3387, Contact: Site Public Contact 787-792-9833, Contact: Site Public Contact 787-763-1296. 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